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How to get fromPalm Desert to San Luis Obispoby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to San Luis Obispo

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There are 6 ways to get from Palm Desert to San Luis Obispo by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Palm Springs International Airport (PSP) to San Luis Obispo County Regional Airport (SBP)plane plane PSP - SBP
    5h 30m
    $308–658

  2. Bus

    cheapest
    1. Take the bus from Indio Bus Station to Los Angeles Union Stationbus bus Greyhound US1000 / ...
    2. Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus bus FlixBus 2005
    9h 27m
    $50–91

  3. Bus, train (Amtrak)

    1. Take the bus from Palm Desert Amtrak Bus Stop to Fullerton Amtrak Stationbus bus Amtrak Thruway Connecting Service
    2. Take the train from Fullerton Amtrak Station to San Luis Obispotrain train Pacific Surfliner
    10h 6m
    $110–219

  4. Drive 306 mi

    1. Drive from Palm Desert to San Luis Obispocar car 306 mi
    5h 31m
    $56–81

  5. Bus, train via Los Angeles

    1. Take the bus from Indio Bus Station to Los Angeles Union Station Arrivalsbus bus FlixBus 2054
    2. Take the train from Los Angeles to San Luis Obispotrain train Coast Starlight / ...
    10h 12m
    $90–186

  6. Bus, train via San Bernardino

    1. Take the bus from Indio, CA to San Bernardino, CAbus bus
    2. Take the train from San Bernardino - Downtown to L.A. Union Stationtrain train
    3. Take the train from Los Angeles to San Luis Obispotrain train
    10h 16m
    $135–245

Palm Desert to San Luis Obispo by bus and foot

Calendar8Weekly Services
Duration9h 27mAverage Duration
Ticket$50Cheapest Price
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Questions & Answers

Map of how to get from Palm Desert to San Luis Obispo.ExpandLaunch map view
  • Distance: 270.4 mi
  • Duration: 5h 30m

What companies run services between Palm Desert, CA, USA and San Luis Obispo, CA, USA?

American Airlines and United Airlines fly from Palm Springs International Airport (PSP) to San Luis Obispo County Regional Airport (SBP) every 4 hours. Alternatively, you can take a bus from Hwy 111 at San Luis Rey to San Luis Obispo Railroad Museum via Hwy 111 & Golf Center Pkwy, Indio Bus Station, and Los Angeles Union Station in around 9h 27m.

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