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How to get fromPalm Harbor to Florida Keysby bus, plane, train, shuttle, car, taxi, or bus (Flixbus, Greyhound)

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There are 9 ways to get from Palm Harbor to Florida Keys by bus, plane, train, shuttle, car, taxi, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport, bus

    best
    1. Take the bus from Alt 19 + Florida Ave to Park St Terminal - Platform - Abus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    3. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    6h 32m
    $112–339

  2. Bus

    cheapest
    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus FlixBus 2421 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    16h 37m
    $69–128

  3. Train, bus

    1. Take the train from Tampa to Miami Amtrak Stationtrain train Floridian
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    12h 20m
    $175–301

  4. Bus, shuttle

    1. Take the bus from Tampa Bus Station to Fort Lauderdale International Airportbus bus FlixBus 2421
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    15h 55m
    $216–278

  5. Drive 392.3 mi

    1. Drive from Palm Harbor to Florida Keyscar car 392.3 mi
    7h 44m
    $72–104

  6. Line 78 bus, line 30 bus to Tampa, fly to Key West International Airport, bus

    1. Take the bus from Main St + Pine Tree Ln to North West Transfer Center Tampabus bus
    2. Take the bus from Northwest Transfer Center to Airport Rental Car Centerbus bus
    3. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    4. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    7h 43m
    $149–491

  7. Taxi, train, train to Orlando, fly to Key West International Airport, bus

    1. Take the taxi from Palm Harbor to Tampataxi taxi
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    3. Take the train from Kissimmee to Sand Lake Roadtrain train
    4. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    8h 42m
    $237–873

  8. Fly Tampa to Miami International Airport, shuttle

    1. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 13m
    $809–1,291

  9. Train, bus via West Palm Beach

    1. Take the train from Tampa to West Palm Beach Amtrak Stationtrain train
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    12h 55m
    $141–248

Palm Harbor to Florida Keys by bus, foot, and shuttle

Calendar14Weekly Services
Duration15h 55mAverage Duration
Ticket$216Cheapest Price
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Questions & Answers

Map of how to get from Palm Harbor to Florida Keys.ExpandLaunch map view
  • Distance: 281.3 mi
  • Duration: 6h 32m

What companies run services between Palm Harbor, FL, USA and Florida Keys, FL, USA?

You can take a bus from Us Hwy 19 N + 33626 to Florida Keys via Main St + Pine Tree Ln, Northwest Transfer Center, Tampa Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 37m.

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