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How to get fromPalm Harbor to Florida Keysby bus, plane, train, shuttle, car, taxi, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Palm Harbor to Florida Keys by bus, plane, train, shuttle, car, taxi, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Saint Petersburg–Clearwater International Airport, fly, bus

    best
    1. Take the bus from Alt 19 + Florida Ave to Park St Terminal - Platform - Abus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    3. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    6h 33m
    $117–339

  2. Drive 392.3 mi

    cheapest
    1. Drive from Palm Harbor to Florida Keyscar car 392.3 mi
    7h 44m
    $72–104

  3. Train, bus

    1. Take the train from Tampa to Miami Amtrak Stationtrain train Floridian
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    12h 20m
    $187–316

  4. Bus, shuttle

    1. Take the bus from Tampa Bus Station to Fort Lauderdale International Airportbus bus FlixBus 2421
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus To the Keys
    15h 27m
    $221–283

  5. Line 78 bus, line 30 bus to Tampa, fly, bus

    1. Take the bus from Main St + Pine Tree Ln to North West Transfer Center Tampabus bus
    2. Take the bus from Northwest Transfer Center to TPA Internat'l Airport Post Officebus bus
    3. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    4. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    8h 4m
    $154–491

  6. Taxi, train, train to Orlando, fly, bus

    1. Take the taxi from Palm Harbor to Tampataxi taxi
    2. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    3. Take the train from Kissimmee to Sand Lake Roadtrain train
    4. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5. Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus bus
    8h 34m
    $236–878

  7. Train, bus via West Palm Beach

    1. Take the train from Tampa to West Palm Beach Amtrak Stationtrain train
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    12h 55m
    $153–263

  8. Bus

    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus FlixBus 2421 / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    16h 30m
    $76–143

Palm Harbor to Florida Keys by bus, foot, and shuttle

Calendar21Weekly Services
Duration15h 27mAverage Duration
Ticket$221Cheapest Price
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Questions & Answers

Map of how to get from Palm Harbor to Florida Keys.ExpandLaunch map view
  • Distance: 281.3 mi
  • Duration: 6h 33m

What companies run services between Palm Harbor, FL, USA and Florida Keys, FL, USA?

You can take a bus from Us Hwy 19 N + 33626 to Florida Keys via Sr 580 + Summerdale, Northwest Transfer Center, Marion Transit Center, Tampa Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h 30m.

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