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How to get fromPalm Harbor to Great Smoky Mountainsby plane, car, train, or bus

Find Transport to Great Smoky Mountains

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There are 10 ways to get from Palm Harbor to Great Smoky Mountains by plane, car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Saint Petersburg–Clearwater International Airport to Asheville Regional Airport, drive

    best
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL)plane plane PIE - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 21m
    $79–377

  2. Train, bus, drive

    1. Take the train from Tampa to Carytrain train
    2. Take the train from Cary to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    24h 50m
    $348–678

  3. Bus, drive

    1. Take the bus from Tampa Bus Station to Orlando Bus Stationbus bus
    2. Take the bus from Orlando Bus Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    26h 15m
    $163–287

  4. Drive 610 mi

    1. Drive from Palm Harbor to Great Smoky Mountainscar car 610 mi
    12h 6m
    $112–161

  5. Fly Saint Petersburg–Clearwater International Airport to Mcghee Tyson Airport, drive

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Mcghee Tyson Airport (TYS)plane plane PIE - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 9m
    $125–671

  6. Drive to Orlando Sanford, fly to Mcghee Tyson Airport, drive

    1. Drive from Palm Harbor to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h
    $143–699

  7. Train to Orlando, fly to Mcghee Tyson Airport, drive

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train
    2. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 59m
    $203–750

  8. Fly Tampa to Greenville–Spartanburg International Airport, drive

    1. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    8h 45m
    $121–372

  9. Fly Tampa to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Tampa (TPA) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane TPA - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    9h 29m
    $232–662

  10. Fly Saint Petersburg–Clearwater International Airport to Greenville–Spartanburg International Airport, drive

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Greenville–Spartanburg International Airport (GSP)plane plane PIE - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    7h 14m
    $114–540

Saint Petersburg–Clearwater International Airport (PIE) to Asheville Regional Airport (AVL) flights

Calendar8Weekly Planes
Duration1h 39mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from Palm Harbor to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 622.2 mi
  • Duration: 6h 21m

What companies run services between Palm Harbor, FL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Palm Harbor to Great Smoky Mountains. However, you can take the line 91 bus to Park St Terminal - Platform - A, take the line 52 bus to 49Th St N + 148Th Ave, walk to Saint Petersburg–Clearwater International Airport (PIE) airport, fly to Asheville Regional Airport (AVL), then drive to Great Smoky Mountains. Alternatively, you can take a vehicle from Palm Harbor to Great Smoky Mountains via Tampa, Cary, Greensboro, Greensboro Bus Stop, and Asheville, NC in around 24h 50m.

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