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How to get fromPalm Harbor to Key Westby bus, plane, ferry, train, car, shuttle, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Palm Harbor to Key West by bus, plane, ferry, train, car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Saint Petersburg–Clearwater International Airport, fly

    best
    1. Take the bus from Alt 19 + Florida Ave to Park St Terminal - Platform - Abus bus
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    3h 46m
    $46–258

  2. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    12h 36m
    $197–228

  3. Train, bus

    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    13h 38m
    $151–266

  4. Drive 407.7 mi

    1. Drive from Palm Harbor to Key Westcar car 407.7 mi
    8h 7m
    $75–108

  5. Line 78 bus to Tampa, fly

    1. Take the bus from Main St + Pine Tree Ln to North West Transfer Center Tampabus bus
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    5h
    $93–440

  6. Bus, shuttle

    1. Take the bus from Tampa Bus Station to Fort Lauderdale International Airportbus bus FlixBus 2421
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key West, FLshuttle bus To the Keys
    16h 18m
    $226–298

  7. Bus

    1. Take the bus from Tampa Bus Station to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    17h 23m
    $69–133

Palm Harbor to Key West by bus, foot, and shuttle

Calendar14Weekly Services
Duration16h 18mAverage Duration
Ticket$226Cheapest Price
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Questions & Answers

Map of how to get from Palm Harbor to Key West.ExpandLaunch map view
  • Distance: 262.1 mi
  • Duration: 3h 46m

What companies run services between Palm Harbor, FL, USA and Key West, FL, USA?

You can take a bus from Us Hwy 19 N + 33626 to N Roosevelt & 3rd Street via Main St + Pine Tree Ln, Northwest Transfer Center, Tampa Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 17h 23m.

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