There are 7 ways to get from Palo Alto to Irvine by plane, bus (Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Norman Y. Mineta San José International Airport
best- Fly from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA)plane SJC - SNA
3h 3m$198–809Bus via Westminster, CA - ABC Supermarket
cheapest- Take the bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarketbus San Jose
11h 21m$52–69Bus
- Take the bus from San Jose Diridon Station to Anaheim Regional Transportation Intermodal Centerbus Greyhound US0831
11h 20m$62–128Train
- Take the train from San Jose to Los Angelestrain Coast Starlight
- Take the train from L.A. Union Station to Tustintrain OC Line
14h 15m$143–298Drive 394.6 mi
- Drive from Palo Alto to Irvinecar 394.6 mi
6h 42m$72–104Caltrain to San Francisco International Airport, fly
- Take the train from California Avenue Caltrain Northbound to Millbrae Caltrain Northboundtrain
- Fly from San Francisco International Airport (SFO) to John Wayne Airport Orange County (SNA)plane SFO - SNA
3h 19m$194–768Train to Oakland International Airport, fly
- Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain
- Fly from Oakland International Airport (OAK) to John Wayne Airport Orange County (SNA)plane OAK - SNA
4h 47m$259–783
Palo Alto to Irvine by train and bus
Questions & Answers
The cheapest way to get from Palo Alto to Irvine is to bus via Westminster, CA - ABC Supermarket which costs $50 - $70 and takes 11h 21m.
The fastest way to get from Palo Alto to Irvine is to fly which takes 3h 3m and costs $190 - $850.
No, there is no direct bus from Palo Alto station to Irvine. However, there are services departing from San Jose Diridon Station and arriving at Main-Paseo Westpark via Artic - Dock 4. The journey, including transfers, takes approximately 11h 20m.
No, there is no direct train from Palo Alto to Irvine. However, there are services departing from California Avenue Caltrain Southbound and arriving at Tustin via San Jose and L.A. Union Station. The journey, including transfers, takes approximately 14h 15m.
The distance between Palo Alto and Irvine is 361 miles. The road distance is 396.9 miles.
The best way to get from Palo Alto to Irvine without a car is to bus which takes 11h 20m and costs $60 - $130.
It takes approximately 3h 3m to get from Palo Alto to Irvine, including transfers.
Palo Alto to Irvine bus services, operated by Jefferson Lines, depart from San Jose Diridon Station.
Palo Alto to Irvine train services, operated by Amtrak, depart from San Jose station.
The best way to get from Palo Alto to Irvine is to fly which takes 3h 3m and costs $190 - $850. Alternatively, you can bus, which costs $60 - $130 and takes 11h 20m, you could also train, which costs $140 - $300 and takes 14h 15m.
What companies run services between Palo Alto, CA, USA and Irvine, CA, USA?
Southwest Airlines flies from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, Jefferson Lines operates a bus from San Jose Diridon Station to Anaheim Regional Transportation Intermodal Center once daily. Tickets cost $85–130 and the journey takes 8h 40m. Greyhound USA also services this route once daily.
- Website
- southwest.com
Flights from Norman Y. Mineta San José International Airport to John Wayne Airport Orange County
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $55–360
Flights from San Francisco International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- $70–380
Flights from Oakland International Airport to John Wayne Airport Orange County
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–390
Flights from Oakland International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 3h 25m
- When
- Saturday
- Estimated price
- $85–450
- Website
- alaskaair.com
Flights from San Francisco International Airport to John Wayne Airport Orange County
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $100–300
- Website
- united.com
Flights from San Francisco International Airport to John Wayne Airport Orange County
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $50–320
- Website
- flyfrontier.com
Flights from San Francisco International Airport to John Wayne Airport Orange County
- Ave. Duration
- 1h 37m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–290
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Jose to Los Angeles
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
Train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtrak
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $12–24
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from L.A. Union Station to Tustin
- Ave. Duration
- 1h 1m
- Frequency
- Every 3 hours
- Estimated price
- $8–12
- Website
- https://metrolinktrains.com
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from California Avenue Caltrain Northbound to Millbrae Caltrain Northbound
- Ave. Duration
- 32 min
- Frequency
- Every 30 minutes
- Estimated price
- $5–7
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $5–7
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from San Jose Diridon Station to Anaheim Regional Transportation Intermodal Center
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $85–130
- Book at
- https://www.jeffersonlines.com
- Adult
- $85–130
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from San Jose Diridon Station to Anaheim Regional Transportation Intermodal Center
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
- Phone
- +1 714-839-3500
- [email protected]
- Website
- xedohoang.com
Bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarket
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $45–60
- Book at
- https://www.gotobus.com/hoangexpress/
- Website
- https://xedohoang.com/en
- Adult One-way
- $45–60
- Phone
- +1 714-839-3500
- [email protected]
- Website
- xedohoang.com
Bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarket
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $48–52
- Schedules at
- xedohoang.com
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More Questions & Answers
Palo Alto to Irvine bus services, operated by Jefferson Lines, arrive at Anaheim Regional Transportation Intermodal Center station.
Palo Alto to Irvine train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Palo Alto to Irvine is 397 miles. It takes approximately 6h 42m to drive from Palo Alto to Irvine.
There are 1576+ hotels available in Irvine.



















