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How to get fromPalo Alto to Louisvilleby plane, bus (Greyhound, Flixbus), subway, train, bus, or car

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There are 7 ways to get from Palo Alto to Louisville by plane, bus (Greyhound, Flixbus), subway, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Francisco International Airport to Louisville International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Louisville International Airport (SDF)plane plane SFO - SDF
    7h 24m
    $215–621

  2. Bus

    1. Take the bus from San Jose Diridon Station to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 9h
    $405–761

  3. BART, train, bus

    1. Take the subway from Millbrae to Richmondsubway subway
    2. Take the train from Richmond to Chicago Union Stationtrain train
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    2d 15h
    $814–1,679

  4. Drive 2,331.9 mi

    1. Drive from Palo Alto to Louisvillecar car 2,331.9 mi
    36h 40m
    $426–615

  5. Fly Norman Y. Mineta San José International Airport to Louisville International Airport

    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Louisville International Airport (SDF)plane plane SJC - SDF
    9h 10m
    $219–912

  6. Train to Oakland International Airport, fly to Louisville International Airport

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to Louisville International Airport (SDF)plane plane OAK - SDF
    10h 28m
    $250–987

  7. Fly San Francisco International Airport to Covington, bus

    1. Fly from San Francisco International Airport (SFO) to Covington (CVG)plane plane SFO - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    10h 10m
    $265–665

Palo Alto to Louisville by train and bus

Calendar7Weekly Services
Duration2d 9hAverage Duration
Ticket$405Cheapest Price
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Questions & Answers

Map of how to get from Palo Alto to Louisville.ExpandLaunch map view
  • Distance: 2,011.3 mi
  • Duration: 7h 24m

What companies run services between Palo Alto, CA, USA and Louisville, KY, USA?

Breeze Airways, Southwest Airlines, and three other airlines fly from San Francisco International Airport (SFO) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a train from California Avenue Caltrain Southbound to Louisville, KY via San Jose Diridon Caltrain Southbound, San Jose Diridon Station, Los Angeles Union Station, St Louis Bus Station, and Evansville, IN in around 2d 9h.

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