Rome2Rio

How to get fromPalo Alto to Santa Anaby plane, bus, train (Amtrak), car, train, or bus (Greyhound)

Find Transport to Santa Ana

See all options

There are 7 ways to get from Palo Alto to Santa Ana by plane, bus, train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Norman Y. Mineta San José International Airport

    best
    1. Fly from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA)plane plane SJC - SNA
    3h 13m
    $227–844

  2. Line 22 bus, bus

    cheapest
    1. Take the bus from El Camino & Churchill to Tully & Kingbus bus 22
    2. Take the bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarketbus bus San Jose
    10h 5m
    $50–67

  3. Train (Amtrak)

    1. Take the train from San Jose to Los Angelestrain train Coast Starlight
    2. Take the train from Los Angeles to Santa Anatrain train Pacific Surfliner
    13h 55m
    $146–309

  4. Drive 387.1 mi

    1. Drive from Palo Alto to Santa Anacar car 387.1 mi
    6h 33m
    $71–103

  5. Caltrain to San Francisco International Airport, fly

    1. Take the train from California Avenue Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    2. Fly from San Francisco International Airport (SFO) to John Wayne Airport Orange County (SNA)plane plane SFO - SNA
    3h 29m
    $223–803

  6. Train to Oakland International Airport, fly

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to John Wayne Airport Orange County (SNA)plane plane OAK - SNA
    4h 56m
    $288–818

  7. Bus

    1. Take the bus from San Jose Diridon Station to Santa Ana Bus Stopbus bus Greyhound US0831
    10h 30m
    $60–126

Palo Alto to Santa Ana by bus

Calendar14Weekly Buses
Duration10h 5mAverage Duration
Ticket$50Cheapest Price
See schedules

Questions & Answers

Map of how to get from Palo Alto to Santa Ana.ExpandLaunch map view
  • Distance: 365.1 mi
  • Duration: 3h 13m

What companies run services between Palo Alto, CA, USA and Santa Ana, CA, USA?

Southwest Airlines flies from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, you can take a bus from El Camino & Churchill to 1St-Main via Tully & King, San Jose, CA - Huong Lan Sandwich, Westminster, CA - ABC Supermarket, and Bolsa-Magnolia in around 10h 5m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers