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How to get fromPalo Alto to Santa Anaby train, plane, bus, train (Amtrak), car, or bus (Greyhound)

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There are 9 ways to get from Palo Alto to Santa Ana by train, plane, bus, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Caltrain to Norman Y. Mineta San José International Airport, fly to John Wayne Airport Orange County

    best
    1. Take the train from California Avenue Caltrain Southbound to Santa Clara Caltrain Southboundtrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA)plane plane SJC - SNA
    4h 6m
    $510–811

  2. Line 22 bus, bus

    cheapest
    1. Take the bus from El Camino & Churchill to Tully & Kingbus bus 22
    2. Take the bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarketbus bus San Jose
    10h 5m
    $50–67

  3. Train (Amtrak)

    1. Take the train from San Jose to Los Angelestrain train Coast Starlight
    2. Take the train from Los Angeles to Santa Anatrain train Pacific Surfliner
    13h 55m
    $254–396

  4. Drive  387.1 mi

    1. Drive from Palo Alto to Santa Anacar car 387.1 mi
    6h 33m
    $64–93

  5. Caltrain to San Francisco International Airport, fly to John Wayne Airport Orange County

    1. Take the train from California Avenue Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    2. Fly from San Francisco International Airport (SFO) to John Wayne Airport Orange County (SNA)plane plane SFO - SNA
    4h 18m
    $116–350

  6. Fly Norman Y. Mineta San José International Airport to Long Beach Airport, bus

    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Long Beach Airport (LGB)plane plane SJC - LGB
    2. Take the bus from Long Beach Downtown Transit Gallery to Santa Ana Bus Stopbus bus
    6h 4m
    $58–326

  7. Train to Oakland International Airport, fly to John Wayne Airport Orange County

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to John Wayne Airport Orange County (SNA)plane plane OAK - SNA
    5h 50m
    $239–796

  8. Fly Norman Y. Mineta San José International Airport to Burbank Bob Hope Airport, train

    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Burbank Bob Hope Airport (BUR)plane plane SJC - BUR
    2. Take the train from Los Angeles to Santa Anatrain train
    6h 15m
    $83–389

  9. Bus (Greyhound)

    1. Take the bus from San Jose Diridon Station to Santa Ana Bus Stopbus bus Greyhound US0831
    10h 50m
    $75–116

Palo Alto to Santa Ana by bus

Calendar14Weekly Buses
Duration10h 5mAverage Duration
Ticket$50Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Palo Alto to Santa Ana.ExpandLaunch map view
  • Distance: 364.7 mi
  • Duration: 4h 6m

What companies run services between Palo Alto, CA, USA and Santa Ana, CA, USA?

You can take a bus from El Camino & Churchill to 1St-Main via Tully & King, San Jose, CA - Huong Lan Sandwich, Westminster, CA - ABC Supermarket, and Bolsa-Magnolia in around 10h 5m. Alternatively, you can take a train from California Avenue Caltrain Southbound to Santa Ana via San Jose Diridon Caltrain Southbound, San Jose, and Los Angeles in around 13h 55m.

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