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How to get fromPalo Alto to St. Louisby plane, bus (Greyhound, Flixbus), subway, train, bus, or car

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There are 7 ways to get from Palo Alto to St. Louis by plane, bus (Greyhound, Flixbus), subway, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Francisco International Airport

    best
    1. Fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL)plane plane SFO - STL
    6h 15m
    $147–411

  2. Bus

    1. Take the bus from San Jose Diridon Station to Los Angeles Union Stationbus bus Greyhound US0831 / ...
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus Greyhound US1210
    2d 1h
    $355–716

  3. BART, train, bus

    1. Take the subway from Millbrae to Richmondsubway subway
    2. Take the train from Richmond to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    4. Take the train from Springfield to St. Louistrain train
    2d 10h
    $788–1,648

  4. Drive 2,073.7 mi

    1. Drive from Palo Alto to St. Louiscar car 2,073.7 mi
    32h 26m
    $379–547

  5. Fly from Norman Y. Mineta San José International Airport

    1. Fly from Norman Y. Mineta San José International Airport (SJC) to Lambert–St. Louis International Airport (STL)plane plane SJC - STL
    7h 56m
    $211–862

  6. Train to Oakland International Airport, fly

    1. Take the train from Santa Clara Amtrak to Oakland Coliseum/Airport Amtraktrain train
    2. Fly from Oakland International Airport (OAK) to Lambert–St. Louis International Airport (STL)plane plane OAK - STL
    9h 30m
    $232–936

  7. Bus, train

    1. Take the bus from San Jose to Los Angelesbus bus Ans 6241
    2. Take the train from Los Angeles to St. Louistrain train Texas Eagle
    2d 18h
    $845–1,736

Palo Alto to St. Louis by train and bus

Calendar21Weekly Services
Duration2d 1hAverage Duration
Ticket$355Cheapest Price
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Questions & Answers

Map of how to get from Palo Alto to St. Louis.ExpandLaunch map view
  • Distance: 1,766 mi
  • Duration: 6h 15m

What companies run services between Palo Alto, CA, USA and St. Louis, MO, USA?

United Airlines, Southwest Airlines, and Delta fly from San Francisco International Airport (SFO) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a train from California Avenue Caltrain Southbound to St Louis Bus Station via San Jose Diridon Caltrain Southbound, San Jose Diridon Station, and Los Angeles Union Station in around 2d 1h.

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