Rome2Rio

Plan your Panama City Itinerary with Real Train, Bus and Car Routes

Panama City travel plans with the routes already figured out

Rome2Rio itineraries for Panama City are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.

1 day

Highlights

  • National Theatre of Panama
  • Biomuseo
  • Mercado de Mariscos

Plaza Paitilla Inn

8.9View hotel
See full itinerary

2 days

Highlights

  • Mercado de Mariscos
  • Biomuseo
  • Causeway Islands

JW Marriott Panama

8.9View hotel

Must-see Panama

Plot your journey across Panama, visiting its many must-see destinations. With just a short train ride or scenic drive, you can journey from one region to another.

Popular cities in Panama to visit