There are 7 ways to get from Panama City Beach to Cancún by plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Northwest Florida Beaches International Airport
best- Fly from Northwest Florida Beaches International Airport (ECP) to Cancún International Airport (CUN)plane ECP - CUN
6h 17m$2,347–8,198Drive to Destin–Fort Walton Beach Airport, fly
cheapest- Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Cancún International Airport (CUN)plane VPS - CUN
7h 18m$1,619–6,886Bus
- Take the bus from Panama City Beach Bus Station to Houston Bus Stationbus
- Take the bus from Houston Bus Station to McAllen Central Stationbus
- Take the bus from Reynosa to Coatzacoalcosbus
- Take the bus from Coatzacoalcos to Cancúnbus
2d 10h$5,613–9,442Drive 3,754.4 km
- Drive from Panama City Beach to Cancúncar 3,754.4 km
45h 21m$7,220–10,428Drive to Dothan Regional Airport, fly
- Drive from Panama City Beach to Dothan Regional Airport (DHN)car
- Fly from Dothan Regional Airport (DHN) to Cancún International Airport (CUN)plane DHN - CUN
8h 19m$1,729–7,045Bus via Villahermosa
- Take the bus from Panama City Beach Bus Station to Houston Bus Stationbus
- Take the bus from Houston Bus Station to McAllen Central Stationbus
- Take the bus from Reynosa to Villahermosabus
- Take the bus from Villahermosa to Terminal de Autobuses ADO Cancúnbus
2d 14h$6,393–11,792Bus via San Luis Potosí
- Take the bus from Panama City Beach Bus Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to McAllen Central Stationbus
- Take the bus from McAllen Central Station to San Luis Potosíbus
- Take the bus from San Luis Potosí to Puebla CAPUbus
- Take the bus from Puebla Capu to Terminal de Autobuses ADO Cancúnbus
2d 22h$7,363–12,792
Northwest Florida Beaches International Airport (ECP) to Cancún International Airport (CUN) flights
Questions & Answers
The cheapest way to get from Panama City Beach to Cancún is to drive and fly which costs $1600 - $7000 and takes 7h 18m.
The fastest way to get from Panama City Beach to Cancún is to fly which takes 6h 17m and costs $2300 - $8500.
No, there is no direct bus from Panama City Beach station to Cancún. However, there are services departing from Panama City Beach Bus Station and arriving at Cancún via Houston Bus Station, McAllen Central Station, Reynosa and Coatzacoalcos. The journey, including transfers, takes approximately 2 days 10h.
The distance between Panama City Beach and Cancún is 1078 km. The road distance is 3754.4 km.
The best way to get from Panama City Beach to Cancún without a car is to bus which takes 2 days 10h and costs $5500 - $9500.
It takes approximately 6h 17m to get from Panama City Beach to Cancún, including transfers.
Panama City Beach to Cancún bus services, operated by Greyhound USA, depart from Panama City Beach Bus Station.
The best way to get from Panama City Beach to Cancún is to fly which takes 6h 17m and costs $2300 - $8500. Alternatively, you can bus, which costs $5500 - $9500 and takes 2 days 10h.
Panama City Beach to Cancún bus services, operated by Greyhound USA, arrive at Houston Bus Station.
Yes, the driving distance between Panama City Beach to Cancún is 3754 km. It takes approximately 45h 21m to drive from Panama City Beach to Cancún.
What companies run services between Panama City Beach, FL, USA and Cancún, Mexico?
Delta, Southwest Airlines, and two other airlines fly from Northwest Florida Beaches International Airport (ECP) to Cancún International Airport (CUN) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Cancún via Panama City Beach Bus Station, Houston Bus Station, McAllen Central Station, Reynosa, and Coatzacoalcos in around 2d 10h.
- Website
- delta.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $1,400–7,000
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $1,400–7,000
Flights from Dothan Regional Airport to Cancún International Airport via Atlanta
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $1,400–6,500
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Charlotte
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $1,800–8,000
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $2,000–8,500
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Miami
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $1,400–6,500
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $2,000–8,500
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Charlotte
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $1,800–8,000
- Website
- southwest.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $1,700–7,500
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Nashville
- Ave. Duration
- 5h 25m
- When
- Saturday and Sunday
- Estimated price
- $1,800–8,000
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via St. Louis
- Ave. Duration
- 6h 20m
- When
- Sunday
- Estimated price
- $2,200–9,000
- Website
- united.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Houston
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $1,700–7,500
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Houston Bus Station
- Ave. Duration
- 13h 40m
- Frequency
- Twice daily
- Estimated price
- $1,600–3,100
- Website
- Greyhound
Bus from Houston Bus Station to McAllen Central Station
- Ave. Duration
- 7h
- Frequency
- 3 times a day
- Estimated price
- $900–1,800
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Houston Bus Station
- Ave. Duration
- 13h 40m
- Frequency
- Twice daily
- Estimated price
- $1,600–3,100
- Website
- Greyhound
Bus from Houston Bus Station to McAllen Central Station
- Ave. Duration
- 7h
- Frequency
- 3 times a day
- Estimated price
- $900–1,800
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Houston Bus Station
- Ave. Duration
- 13h 40m
- Frequency
- Twice daily
- Estimated price
- $1,600–3,100
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Houston Bus Station to McAllen Central Station
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $950–1,700
- Schedules at
- Flixbus USA
Bus from Houston Bus Station to McAllen Central Station
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $950–1,700
- Schedules at
- Flixbus USA
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Reynosa to Coatzacoalcos
- Ave. Duration
- 18h 59m
- Frequency
- 4 times a day
- Estimated price
- $2,300–3,500
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Bus from Reynosa to Villahermosa
- Ave. Duration
- 22h 50m
- Frequency
- Twice daily
- Estimated price
- $2,700–3,900
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Bus from Villahermosa to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 14h 32m
- Frequency
- Every 30 minutes
- Estimated price
- $1,600–2,400
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
Bus from Puebla Capu to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 26h
- Frequency
- Twice daily
- Estimated price
- $2,100–4,400
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 998 398 8466
- [email protected]
- Website
- Vive Mexico
Bus from Coatzacoalcos to Cancún
- Ave. Duration
- 15h
- Frequency
- Once daily
- Estimated price
- $650–850
- Schedules at
- Vive Mexico
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Villahermosa to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 15h 50m
- Frequency
- 5 times a day
- Estimated price
- $1,500–2,700
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Villahermosa to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 16h 10m
- Frequency
- 3 times a day
- Estimated price
- $950–1,500
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to McAllen Central Station
- Ave. Duration
- 7h
- Frequency
- Once daily
- Estimated price
- $1,200–1,600
- Schedules at
- Omnibus Express
- Phone
- +1 800 923 1799
- [email protected]
- Website
- Omnibus Express (OMEX VIP)
Bus from McAllen Central Station to San Luis Potosí
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $1,100–1,800
- Schedules at
- Omnibus Express (OMEX VIP)
- Phone
- +52 800 800 0386
- [email protected]
- Website
- ETN Turistar
Bus from San Luis Potosí to Puebla CAPU
- Ave. Duration
- 7h 16m
- Frequency
- 5 times a day
- Estimated price
- $1,200–1,700
- Website
- ETN Turistar
Want to know more about travelling around Mexico
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