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How to get fromPanama City Beach to Charleston Amtrak Stationby plane, bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Panama City Beach to Charleston Amtrak Station by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Northwest Florida Beaches International Airport

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Charleston International Airport (CHS)plane plane ECP - CHS
    5h 28m
    $123–448

  2. Drive to Destin–Fort Walton Beach Airport, fly

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Charleston International Airport (CHS)plane plane VPS - CHS
    6h 51m
    $80–400

  3. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus Greyhound US0760S
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train Silver Meteor
    12h 54m
    $121–249

  4. Drive 448.1 mi

    1. Drive from Panama City Beach to Charleston Amtrak Stationcar car 448.1 mi
    9h 3m
    $82–119

  5. Drive to Dothan Regional Airport, fly

    1. Drive from Panama City Beach to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Charleston International Airport (CHS)plane plane DHN - CHS
    6h 58m
    $81–389

  6. Bus, train via Tallahassee

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    13h 4m
    $125–253

  7. Bus (Greyhound)

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    3. Take the bus from Sumter Bus Stop to Charleston Bus Stationbus bus
    18h 39m
    $114–226

Northwest Florida Beaches International Airport (ECP) to Charleston International Airport (CHS) flights

Calendar61Weekly Planes
Duration4h 47mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Charleston Amtrak Station.ExpandLaunch map view
  • Distance: 405.4 mi
  • Duration: 5h 28m

What companies run services between Panama City Beach, FL, USA and Charleston Amtrak Station, SC, USA?

Delta, American Airlines, and Southwest Airlines fly from Northwest Florida Beaches International Airport (ECP) to Charleston International Airport (CHS) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Charleston Bus Station via Panama City Beach Bus Station, Jacksonville, and Sumter Bus Stop in around 18h 39m.

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