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How to get fromPanama City Beach to Clevelandby plane, bus (Greyhound), bus, train, or car

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There are 6 ways to get from Panama City Beach to Cleveland by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Northwest Florida Beaches International Airport

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Cleveland-Hopkins International Airport (CLE)plane plane ECP - CLE
    4h 56m
    $157–617

  2. Drive to Destin–Fort Walton Beach Airport, fly

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Cleveland-Hopkins International Airport (CLE)plane plane VPS - CLE
    5h 56m
    $114–569

  3. Bus

    1. Take the bus from Panama City Beach Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Toledo Bus Stopbus bus
    4. Take the bus from Toledo to Clevelandbus bus
    29h 34m
    $218–366

  4. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus Greyhound US0760S
    2. Take the train from Jacksonville to Cleveland Amtraktrain train Floridian
    37h
    $706–1,184

  5. Drive  973.9 mi

    1. Drive from Panama City Beach to Clevelandcar car 973.9 mi
    16h 54m
    $178–257

  6. Drive to Dothan Regional Airport, fly

    1. Drive from Panama City Beach to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Cleveland-Hopkins International Airport (CLE)plane plane DHN - CLE
    7h 41m
    $115–578

Northwest Florida Beaches International Airport (ECP) to Cleveland-Hopkins International Airport (CLE) flights

Calendar78Weekly Planes
Duration5h 16mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Panama City Beach to Cleveland.ExpandLaunch map view
  • Distance: 825.1 mi
  • Duration: 4h 56m

What companies run services between Panama City Beach, FL, USA and Cleveland, OH, USA?

Delta, Southwest Airlines, and American Airlines fly from Northwest Florida Beaches International Airport (ECP) to Cleveland-Hopkins International Airport (CLE) every 2 hours. Alternatively, you can take a vehicle from Panama City Beach to Cleveland via Panama City Beach Bus Station, Mobile Bus Station, Montgomery Intermodal Center, and Toledo in around 29h 34m.

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Need to know: Greyhound

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