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How to get fromPanama City Beach to Columbiaby plane, bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Panama City Beach to Columbia by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Columbia

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Columbia (CAE)plane plane ECP - CAE
    5h 47m
    $111–406

  2. Drive to Destin–Fort Walton Beach Airport, fly to Columbia

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia (CAE)plane plane VPS - CAE
    6h 9m
    $68–358

  3. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus Greyhound US0760S
    2. Take the train from Jacksonville to Columbia Stationtrain train Floridian
    14h 18m
    $136–284

  4. Drive 428.7 mi

    1. Drive from Panama City Beach to Columbiacar car 428.7 mi
    9h 4m
    $79–113

  5. Fly Northwest Florida Beaches International Airport to Augusta Regional Airport At Bush Field, bus

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Augusta Regional Airport At Bush Field (AGS)plane plane ECP - AGS
    2. Take the bus from Augusta to Columbia, SCbus bus
    7h 39m
    $165–476

  6. Bus

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    3. Take the bus from James E Clyburn Intermodal Transportation Center to Assembly Senate Northbus bus 44
    16h 50m
    $97–183

Northwest Florida Beaches International Airport (ECP) to Columbia (CAE) flights

Calendar72Weekly Planes
Duration5hAverage Duration
Ticket$56Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Columbia.ExpandLaunch map view
  • Distance: 396.6 mi
  • Duration: 5h 47m

What companies run services between Panama City Beach, FL, USA and Columbia, SC, USA?

American Airlines, Delta, and United Airlines fly from Northwest Florida Beaches International Airport (ECP) to Columbia (CAE) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Assembly Senate North via Panama City Beach Bus Station, Jacksonville, Sumter Bus Stop, and James E Clyburn Intermodal Transportation Center in around 16h 50m.

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