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How to get fromPanama City Beach to Fort Myersby plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Panama City Beach to Fort Myers by plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Ft. Myers

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    6h 24m
    $142–509

  2. Drive 463.6 mi

    cheapest
    1. Drive from Panama City Beach to Fort Myerscar car 463.6 mi
    8h 46m
    $85–123

  3. Bus

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus Greyhound US0799 / ...
    2. Take the bus from Tallahassee to Fort Myersbus bus Houston
    12h 10m
    $107–153

  4. Drive to Destin–Fort Walton Beach Airport, fly to Ft. Myers

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane plane VPS - RSW
    7h 25m
    $99–461

  5. Fly Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport, bus

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Sarasota–Bradenton International Airport (SRQ)plane plane ECP - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    7h 49m
    $167–637

  6. Drive to Destin–Fort Walton Beach Airport, fly to Miami International Airport, bus

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    3. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    7h 37m
    $96–401

  7. Bus via University

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to University of South Florida - 3801 USF Holly Drbus bus
    3. Take the bus from University of South Florida to Fort Myers Bus Stopbus bus
    14h 12m
    $115–223

Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW) flights

Calendar70Weekly Planes
Duration5h 31mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Fort Myers.ExpandLaunch map view
  • Distance: 394.1 mi
  • Duration: 6h 24m

What companies run services between Panama City Beach, FL, USA and Fort Myers, FL, USA?

Delta, American Airlines, and two other airlines fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Fort Myers via Panama City Beach Bus Station, C.K. Steele Plaza Gate 16, N Monroe Street and John Knox Road, and Tallahassee in around 12h 10m.

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