There are 11 ways to get from Panama City Beach to Iowa by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Northwest Florida Beaches International Airport to Omaha
best- Fly from Northwest Florida Beaches International Airport (ECP) to Omaha (OMA)plane ECP - OMA
4h 48m$189–694Drive to Destin–Fort Walton Beach Airport, fly to Quad City International Airport
cheapest- Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Quad City International Airport (MLI)plane VPS - MLI
7h 13m$93–448Bus via Wake Village
- Take the bus from Panama City Beach Bus Station to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Shreveport Bus Stationbus
- Take the bus from Shreveport Bus Station to Texarkanabus
- Take the bus from Texarkana to Kansas Citybus
- Take the bus from Kansas City to Des Moinesbus
29h 59m$277–420Bus, train via New Orleans
- Take the bus from Panama City Beach Bus Station to Mobile Bus Stationbus
- Take the bus from Mobile Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus
33h 35m$558–891Drive 1,063.1 mi
- Drive from Panama City Beach to Des Moinescar 1,063.1 mi
19h 52m$194–281Fly Northwest Florida Beaches International Airport to Des Moines
- Fly from Northwest Florida Beaches International Airport (ECP) to Des Moines (DSM)plane ECP - DSM
5h 13m$162–537Fly Northwest Florida Beaches International Airport to The Eastern Iowa Airport
- Fly from Northwest Florida Beaches International Airport (ECP) to The Eastern Iowa Airport (CID)plane ECP - CID
5h 55m$179–554Drive to Destin–Fort Walton Beach Airport, fly to Des Moines
- Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM)plane VPS - DSM
4h 3m$109–469Fly Northwest Florida Beaches International Airport to Quad City International Airport
- Fly from Northwest Florida Beaches International Airport (ECP) to Quad City International Airport (MLI)plane ECP - MLI
6h 17m$136–496Bus
- Take the bus from Panama City Beach Bus Station to Tallahasseebus
- Take the bus from Tallahassee to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Bloomingtonbus
- Take the bus from Bloomington, IN to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Des Moinesbus
34h 5m$243–417Bus, train
- Take the bus from Panama City Beach Bus Station to Jacksonvillebus
- Take the train from Jacksonville to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
2d 3h$959–1,579
Northwest Florida Beaches International Airport (ECP) to Omaha (OMA) flights
Comparing Your Travel Options
The cheapest way to get from Panama City Beach to Iowa is to drive which costs $190 - $280 and takes 19h 52m.
The fastest way to get from Panama City Beach to Iowa is to drive and fly which takes 4h 3m and costs $100 - $470.
No, there is no direct bus from Panama City Beach station to Iowa. However, there are services departing from Panama City Beach Bus Station and arriving at Des Moines via Baton Rouge Bus Station, Shreveport Bus Station, Texarkana and Kansas City. The journey, including transfers, takes approximately 29h 59m.
The distance between Panama City Beach and Iowa is 975 miles. The road distance is 1069.3 miles.
The best way to get from Panama City Beach to Iowa without a car is to bus via Wake Village which takes 29h 59m and costs $270 - $420.
It takes approximately 4h 48m to get from Panama City Beach to Iowa, including transfers.
Panama City Beach to Iowa bus services, operated by Greyhound USA, depart from Panama City Beach Bus Station.
The best way to get from Panama City Beach to Iowa is to fly which takes 4h 48m and costs $180 - $700. Alternatively, you can bus via Wake Village, which costs $270 - $420 and takes 29h 59m.
Panama City Beach to Iowa bus services, operated by Greyhound USA, arrive at Baton Rouge Bus Station.
Yes, the driving distance between Panama City Beach to Iowa is 1069 miles. It takes approximately 19h 52m to drive from Panama City Beach to Iowa.
What companies run services between Panama City Beach, FL, USA and Iowa, USA?
Southwest Airlines, Delta, and American Airlines fly from Northwest Florida Beaches International Airport (ECP) to Omaha (OMA) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Des Moines via Panama City Beach Bus Station, Baton Rouge Bus Station, Shreveport Bus Station, Texarkana, and Kansas City in around 29h 59m.
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Omaha via Dallas/Ft.Worth
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $130–650
Flights from Northwest Florida Beaches International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $95–480
Flights from Northwest Florida Beaches International Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 16m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–500
Flights from Northwest Florida Beaches International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $110–550
Flights from Northwest Florida Beaches International Airport to The Eastern Iowa Airport via Chicago O'Hare
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $90–460
Flights from Northwest Florida Beaches International Airport to The Eastern Iowa Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $110–550
Flights from Northwest Florida Beaches International Airport to The Eastern Iowa Airport via Charlotte
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $100–490
Flights from Destin–Fort Walton Beach Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 54m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
Flights from Northwest Florida Beaches International Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $110–550
Flights from Northwest Florida Beaches International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 8h 21m
- When
- Every day
- Estimated price
- $95–480
Flights from Destin–Fort Walton Beach Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 52m
- When
- Saturday
- Estimated price
- $85–440
Flights from Destin–Fort Walton Beach Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $95–480
Flights from Destin–Fort Walton Beach Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from Northwest Florida Beaches International Airport to Omaha via Atlanta
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $120–600
Flights from Northwest Florida Beaches International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $90–450
Flights from Northwest Florida Beaches International Airport to The Eastern Iowa Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $85–440
Flights from Destin–Fort Walton Beach Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $90–450
Flights from Destin–Fort Walton Beach Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Northwest Florida Beaches International Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $80–430
Flights from Destin–Fort Walton Beach Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $80–430
- Website
- southwest.com
Flights from Northwest Florida Beaches International Airport to Omaha via St. Louis
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $110–600
Flights from Northwest Florida Beaches International Airport to Omaha via Chicago Midway
- Ave. Duration
- 5h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $130–650
Flights from Northwest Florida Beaches International Airport to Omaha via Dallas
- Ave. Duration
- 5h 15m
- When
- Saturday
- Estimated price
- $130–650
Flights from Northwest Florida Beaches International Airport to Omaha via Nashville
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $110–600
Flights from Northwest Florida Beaches International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 50m
- When
- Tuesday and Wednesday
- Estimated price
- $95–480
- Website
- united.com
Flights from Northwest Florida Beaches International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 7m
- When
- Saturday
- Estimated price
- $95–480
Flights from Northwest Florida Beaches International Airport to Des Moines via Houston
- Ave. Duration
- 7h 39m
- When
- Every day
- Estimated price
- $110–550
Flights from Northwest Florida Beaches International Airport to The Eastern Iowa Airport via Chicago O'Hare
- Ave. Duration
- 5h 12m
- When
- Saturday
- Estimated price
- $90–460
Flights from Northwest Florida Beaches International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $85–450
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Des Moines
- Ave. Duration
- 2h 28m
- When
- Thursday
- Estimated price
- $80–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Champaign-Urbana
- Ave. Duration
- 16h 40m
- Frequency
- Once daily
- Estimated price
- $440–700
- Website
- Amtrak
Train from Jacksonville to Chicago Union Station
- Ave. Duration
- 35h 12m
- Frequency
- Once daily
- Estimated price
- $850–1,400
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Baton Rouge Bus Station
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Baton Rouge Bus Station to Shreveport Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 6 times a week
- Estimated price
- $40–65
- Website
- Greyhound
Bus from Shreveport Bus Station to Texarkana
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–19
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Mobile Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Website
- Greyhound
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Des Moines
- Ave. Duration
- 7h 40m
- Frequency
- Once daily
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Tallahassee
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $16–26
- Website
- Greyhound
Bus from Tallahassee to Atlanta Bus Station
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Indianapolis Union Station to Des Moines
- Ave. Duration
- 9h 50m
- Frequency
- Once daily
- Estimated price
- $75–120
- Website
- Greyhound
Bus from Panama City Beach Bus Station to Jacksonville
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–85
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Texarkana to Kansas City
- Ave. Duration
- 9h 5m
- Frequency
- Twice daily
- Estimated price
- $110–160
- Book at
- Jefferson Lines
- Adult
- $110–160
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 6 times a week
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Tallahassee to Atlanta Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Bloomington
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $75–120
- Schedules at
- Flixbus USA
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Bloomington, IN to Indianapolis Union Station
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $19–55
- Website
- Miller Transportation
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 255+ hotels available in Iowa.












