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How to get fromPanama City Beach to Iowaby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Panama City Beach to Iowa by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Des Moines

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Des Moines (DSM)plane plane ECP - DSM
    4h 59m
    $162–527

  2. Drive to Destin–Fort Walton Beach Airport, fly to Quad City International Airport

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Quad City International Airport (MLI)plane plane VPS - MLI
    7h 14m
    $92–447

  3. Bus via Wake Village

    1. Take the bus from Panama City Beach Bus Station to Baton Rouge Bus Stationbus bus
    2. Take the bus from Baton Rouge Bus Station to Shreveport Bus Stationbus bus
    3. Take the bus from Shreveport Bus Station to Texarkanabus bus
    4. Take the bus from Texarkana to Kansas Citybus bus
    5. Take the bus from Kansas City to Des Moinesbus bus
    29h 59m
    $293–437

  4. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Champaign-Urbanatrain train
    4. Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus bus
    33h 35m
    $568–901

  5. Drive  1,063.1 mi

    1. Drive from Panama City Beach to Des Moinescar car 1,063.1 mi
    19h 52m
    $182–263

  6. Fly Northwest Florida Beaches International Airport to The Eastern Iowa Airport

    1. Fly from Northwest Florida Beaches International Airport (ECP) to The Eastern Iowa Airport (CID)plane plane ECP - CID
    5h 23m
    $179–554

  7. Drive to Destin–Fort Walton Beach Airport, fly to Des Moines

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM)plane plane VPS - DSM
    4h 3m
    $108–458

  8. Fly Northwest Florida Beaches International Airport to Omaha

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Omaha (OMA)plane plane ECP - OMA
    5h 13m
    $199–744

  9. Fly Northwest Florida Beaches International Airport to Quad City International Airport

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Quad City International Airport (MLI)plane plane ECP - MLI
    6h 11m
    $136–496

  10. Bus

    1. Take the bus from Panama City Beach Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    5. Take the bus from Kansas City to Des Moinesbus bus
    32h 14m
    $275–431

Northwest Florida Beaches International Airport (ECP) to Des Moines (DSM) flights

Calendar64Weekly Planes
Duration5h 44mAverage Duration
Ticket$90Cheapest Price
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Comparing Your Travel Options

Map of how to get from Panama City Beach to Iowa.ExpandLaunch map view
  • Distance: 912.4 mi
  • Duration: 4h 59m

What companies run services between Panama City Beach, FL, USA and Iowa, USA?

Delta, Southwest Airlines, and two other airlines fly from Northwest Florida Beaches International Airport (ECP) to Des Moines (DSM) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Des Moines via Panama City Beach Bus Station, Baton Rouge Bus Station, Shreveport Bus Station, Texarkana, and Kansas City in around 29h 59m.

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