There are 5 ways to get from Panama City Beach to Isla Mujeres by plane, ferry, car, car ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Northwest Florida Beaches International Airport to Cancún International Airport, ferry
best- Fly from Northwest Florida Beaches International Airport (ECP) to Cancún International Airport (CUN)plane ECP - CUN
- Take the ferry from Playa Tortugas to Isla Mujeresferry
7h 50m$2,837–9,193Drive to Destin–Fort Walton Beach Airport, fly to Cancún International Airport, ferry
cheapest- Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Cancún International Airport (CUN)plane VPS - CUN
- Take the ferry from Playa Tortugas to Isla Mujeresferry
8h 51m$2,105–7,877Drive, car ferry
- Drive from Panama City Beach to Punta Samcar
- Take the car ferry from Punta Sam to Isla Mujerescarferry Punta Sam
46h 15m$7,792–11,024Drive to Dothan Regional Airport, fly to Cancún International Airport, ferry
- Drive from Panama City Beach to Dothan Regional Airport (DHN)car
- Fly from Dothan Regional Airport (DHN) to Cancún International Airport (CUN)plane DHN - CUN
- Take the ferry from Playa Tortugas to Isla Mujeresferry
9h 52m$2,215–8,037Fly Northwest Florida Beaches International Airport to Cozumel International Airport, ferry, bus
- Fly from Northwest Florida Beaches International Airport (ECP) to Cozumel International Airport (CZM)plane ECP - CZM
- Take the ferry from Cozumel to Playa del Carmenferry
- Take the bus from Playa del Carmen Alterna to Terminal de Autobuses ADO Cancúnbus
- Take the ferry from Playa Tortugas to Isla Mujeresferry
11h 24m$3,602–12,815
Northwest Florida Beaches International Airport (ECP) to Cancún International Airport (CUN) flights
Questions & Answers
The cheapest way to get from Panama City Beach to Isla Mujeres is to drive and fly and ferry which costs $2100 - $8000 and takes 8h 51m.
The fastest way to get from Panama City Beach to Isla Mujeres is to fly and ferry which takes 7h 50m and costs $2800 - $9500.
The distance between Panama City Beach and Isla Mujeres is 1118 km.
It takes approximately 7h 50m to get from Panama City Beach to Isla Mujeres, including transfers.
There are 1643+ hotels available in Isla Mujeres.
What companies run services between Panama City Beach, FL, USA and Isla Mujeres, Mexico?
There is no direct connection from Panama City Beach to Isla Mujeres. However, you can take the taxi to Northwest Florida Beaches International Airport (ECP) airport, fly to Cancún International Airport (CUN), walk to Aeropuerto Internacional de Cancún Terminal 2, take the shuttle to Playa Tortugas, walk to Playa Tortugas, then take the ferry to Isla Mujeres. Alternatively, you can take a vehicle from Panama City Beach to Isla Mujeres via Punta Sam in around 46h 15m.
- Website
- delta.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Atlanta
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $1,400–7,000
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $1,500–7,000
Flights from Dothan Regional Airport to Cancún International Airport via Atlanta
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $1,400–6,500
Flights from Northwest Florida Beaches International Airport to Cozumel International Airport via Atlanta
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $2,100–10,000
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Charlotte
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $1,800–8,000
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $2,000–8,500
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Miami
- Ave. Duration
- 5h 55m
- When
- Every day
- Estimated price
- $1,400–6,500
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $2,000–8,500
Flights from Destin–Fort Walton Beach Airport to Cancún International Airport via Charlotte
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $1,800–8,000
Flights from Northwest Florida Beaches International Airport to Cozumel International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 9m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $2,900–13,000
- Website
- southwest.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $1,700–7,500
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Nashville
- Ave. Duration
- 5h 25m
- When
- Saturday and Sunday
- Estimated price
- $1,800–8,000
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via St. Louis
- Ave. Duration
- 6h 20m
- When
- Sunday
- Estimated price
- $2,200–9,000
- Website
- united.com
Flights from Northwest Florida Beaches International Airport to Cancún International Airport via Houston
- Ave. Duration
- 6h 35m
- When
- Every day
- Estimated price
- $1,700–7,500
Flights from Northwest Florida Beaches International Airport to Cozumel International Airport via Houston
- Ave. Duration
- 8h 12m
- When
- Every day
- Estimated price
- $2,500–11,000
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Playa del Carmen Alterna to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 1h 10m
- Frequency
- Every 20 minutes
- Estimated price
- $110–290
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Playa del Carmen Alterna to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $140–280
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 983 119 9526
- [email protected]
- Website
- facebook.com
Bus from Playa del Carmen Alterna to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $550–600
- Schedules at
- facebook.com
- Phone
- +52 55 4386 4652
- [email protected]
- Website
- ado.com.mx
Bus from Playa del Carmen Alterna to Terminal de Autobuses ADO Cancún
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $110–550
- Schedules at
- ado.com.mx
- Book at
- ado.com.mx
- Phone
- +52 998 460 3084
- [email protected]
- Website
- ultramarferry.com
Ferry from Playa Tortugas to Isla Mujeres
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $220–310
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $280–310
- Adult
- $290
- Child
- $220
Ferry from Playa Tortugas to Isla Mujeres
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $220–310
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $280–310
- Adult
- $290
- Child
- $220
Ferry from Playa Tortugas to Isla Mujeres
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $220–310
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $280–310
- Adult
- $290
- Child
- $220
Ferry from Cozumel to Playa del Carmen
- Ave. Duration
- 40 min
- Frequency
- Every 3 hours
- Estimated price
- $99–376
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $290–320
- Premium Plus Adult
- $316
- Premium Plus Children
- $237
- Residentes Q.Roo
- $188
- INAPAM
- $99
- First Class Adult
- $376
- First Class Children
- $376
Ferry from Playa Tortugas to Isla Mujeres
- Ave. Duration
- 30 min
- Frequency
- Every 3 hours
- Estimated price
- $220–310
- Website
- https://www.ultramarferry.com/en
- Premium Plus
- $280–310
- Adult
- $290
- Child
- $220
- Phone
- +52 998 302 9244
- [email protected]
- Website
- ultracarga.com
Car ferry from Punta Sam to Isla Mujeres
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- $520
- Schedules at
- ultracarga.com
- Phone
- +52 987 872 1588
- [email protected]
- Website
- winjet.mx
Ferry from Cozumel to Playa del Carmen
- Ave. Duration
- 45 min
- Frequency
- Every 3 hours
- Estimated price
- $109–340
- Schedules at
- winjet.mx
- General
- $340
- Handicapped
- $109
- Minor
- $262
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