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How to get fromPanama City Beach to Kentuckyby car, plane, bus (Greyhound, Amtrak), or bus (Greyhound)

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There are 7 ways to get from Panama City Beach to Kentucky by car, plane, bus (Greyhound, Amtrak), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Destin–Fort Walton Beach Airport, fly to Covington

    best
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Covington (CVG)plane plane VPS - CVG
    4h 11m
    $113–618

  2. Drive to Destin–Fort Walton Beach Airport, fly to Louisville International Airport

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Louisville International Airport (SDF)plane plane VPS - SDF
    4h 29m
    $102–569

  3. Bus

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    18h 19m
    $130–241

  4. Drive 629.9 mi

    1. Drive from Panama City Beach to Louisvillecar car 629.9 mi
    11h 4m
    $115–166

  5. Fly Northwest Florida Beaches International Airport to Blue Grass Airport

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Blue Grass Airport (LEX)plane plane ECP - LEX
    6h 28m
    $186–816

  6. Drive to Destin–Fort Walton Beach Airport, fly to Blue Grass Airport

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Blue Grass Airport (LEX)plane plane VPS - LEX
    7h 12m
    $143–768

  7. Bus via Preston @ Vim

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus bus
    19h 11m
    $153–346

Destin–Fort Walton Beach Airport (VPS) to Covington (CVG) flights

Calendar36Weekly Planes
Duration3hAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Kentucky.ExpandLaunch map view
  • Distance: 674.4 mi
  • Duration: 4h 11m

What companies run services between Panama City Beach, FL, USA and Kentucky, USA?

You can take a vehicle from Panama City Beach to Louisville, KY via Panama City Beach Bus Station, Tallahassee, and Nashville in around 18h 19m. Alternatively, Delta, American Airlines, and United Airlines fly from Northwest Florida Beaches International Airport (ECP) to Blue Grass Airport (LEX) every 3 hours.

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