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How to get fromPanama City Beach to Myrtle Beachby plane, bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Panama City Beach to Myrtle Beach by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Northwest Florida Beaches International Airport

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Myrtle Beach (MYR)plane plane ECP - MYR
    4h 20m
    $120–388

  2. Drive to Destin–Fort Walton Beach Airport, fly

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Myrtle Beach (MYR)plane plane VPS - MYR
    5h 13m
    $77–340

  3. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    16h 9m
    $146–293

  4. Drive 540.5 mi

    1. Drive from Panama City Beach to Myrtle Beachcar car 540.5 mi
    11h 9m
    $99–143

  5. Drive to Dothan Regional Airport, fly

    1. Drive from Panama City Beach to Dothan Regional Airport (DHN)car car
    2. Fly from Dothan Regional Airport (DHN) to Myrtle Beach (MYR)plane plane DHN - MYR
    5h 40m
    $78–339

  6. Bus (Greyhound)

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Camdenbus bus
    3. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    19h 9m
    $117–226

Northwest Florida Beaches International Airport (ECP) to Myrtle Beach (MYR) flights

Calendar49Weekly Planes
Duration4h 47mAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Myrtle Beach.ExpandLaunch map view
  • Distance: 484.9 mi
  • Duration: 4h 20m

What companies run services between Panama City Beach, FL, USA and Myrtle Beach, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Northwest Florida Beaches International Airport (ECP) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a vehicle from Panama City Beach to Myrtle Beach Bus Station via Panama City Beach Bus Station, Jacksonville, and Camden in around 19h 9m.

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