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How to get fromPanama City Beach to O'Fallonby plane, train, bus (Greyhound, Flixbus), bus, or car

Find Transport to O'Fallon

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There are 7 ways to get from Panama City Beach to O'Fallon by plane, train, bus (Greyhound, Flixbus), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Lambert–St. Louis International Airport, train

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    4h 18m
    $158–618

  2. Drive to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport

    cheapest
    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    3h 21m
    $102–407

  3. Bus

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    22h 57m
    $144–275

  4. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train
    4. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus
    26h 31m
    $263–555

  5. Drive 746.9 mi

    1. Drive from Panama City Beach to O'Falloncar car 746.9 mi
    12h 57m
    $137–197

  6. Drive to Destin–Fort Walton Beach Airport, fly to Lambert–St. Louis International Airport, train

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    3. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    5h 19m
    $110–570

  7. Bus via New Orleans

    1. Take the bus from Panama City Beach Bus Station to Mobile Bus Stationbus bus
    2. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus
    24h 52m
    $158–310

Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL) flights

Calendar29Weekly Planes
Duration2h 53mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to O'Fallon.ExpandLaunch map view
  • Distance: 696.7 mi
  • Duration: 4h 18m

What companies run services between Panama City Beach, FL, USA and O'Fallon, IL, USA?

You can take a vehicle from Panama City Beach to State @ Lincoln Eb via Panama City Beach Bus Station, Tallahassee, Nashville Bus Station, St Louis Bus Station, CIVIC CENTER station, FAIRVIEW HEIGHTS station, and Fairview Heights Transit Center in around 22h 57m.

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