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How to get fromPanama City Beach to Orangeburgby plane, taxi, bus (Greyhound, Flixbus), car, bus, or train

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There are 6 ways to get from Panama City Beach to Orangeburg by plane, taxi, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Columbia, taxi

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Columbia (CAE)plane plane ECP - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    5h 7m
    $314–1,064

  2. Drive 424.1 mi

    cheapest
    1. Drive from Panama City Beach to Orangeburgcar car 424.1 mi
    9h 25m
    $78–112

  3. Bus

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus Greyhound US0760S
    2. Take the bus from Jacksonville to Orangeburgbus bus FlixBus 2433
    12h 17m
    $93–171

  4. Fly Northwest Florida Beaches International Airport to Augusta Regional Airport At Bush Field, drive

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Augusta Regional Airport At Bush Field (AGS)plane plane ECP - AGS
    2. Drive from Augusta Regional Airport At Bush Field (AGS) to Orangeburgcar car
    5h 50m
    $118–405

  5. Drive to Destin–Fort Walton Beach Airport, fly to Columbia, taxi

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Columbia (CAE)plane plane VPS - CAE
    3. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    5h 28m
    $271–1,016

  6. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the train from Jacksonville to Denmark Amtrak Stationtrain train
    13h 51m
    $190–334

Northwest Florida Beaches International Airport (ECP) to Columbia (CAE) flights

Calendar72Weekly Planes
Duration5hAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Orangeburg.ExpandLaunch map view
  • Distance: 427 mi
  • Duration: 5h 7m

What companies run services between Panama City Beach, FL, USA and Orangeburg, SC, USA?

You can take a vehicle from Panama City Beach to Orangeburg via Panama City Beach Bus Station, Jacksonville, and Orangeburg in around 12h 17m.

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