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How to get fromPanama City Beach to Sanibelby plane, bus, taxi, car, bus (Greyhound), or bus (Greyhound, Flixbus)

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There are 6 ways to get from Panama City Beach to Sanibel by plane, bus, taxi, car, bus (Greyhound), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Northwest Florida Beaches International Airport

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane plane ECP - RSW
    5h 3m
    $214–599

  2. Drive 480 mi

    cheapest
    1. Drive from Panama City Beach to Sanibelcar car 480 mi
    9h 12m
    $88–127

  3. Bus, taxi

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee - FSU - Old St Augustine at Intramural Field to Fort Myers 7-11bus bus
    3. Take the taxi from Fort Myers 7-11 to Sanibeltaxi taxi
    12h 30m
    $202–333

  4. Drive to Destin–Fort Walton Beach Airport, fly

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane plane VPS - RSW
    6h 4m
    $171–551

  5. Bus

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus Greyhound US0799 / ...
    2. Take the bus from Tallahassee to Fort Myersbus bus Houston
    12h 44m
    $167–233

  6. Bus via Oak Ridge

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Orlandobus bus
    3. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    18h 19m
    $131–212

Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW) flights

Calendar70Weekly Planes
Duration5h 31mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to Sanibel.ExpandLaunch map view
  • Distance: 404.1 mi
  • Duration: 5h 3m

What companies run services between Panama City Beach, FL, USA and Sanibel, FL, USA?

Delta, American Airlines, and two other airlines fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a vehicle from Panama City Beach to Sanibel via Panama City Beach Bus Station, C.K. Steele Plaza Gate 16, N Monroe Street and John Knox Road, Tallahassee, and Fort Myers in around 12h 44m.

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