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How to get fromPanama City Beach to South Carolinaby plane, bus, train, car, or taxi

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There are 8 ways to get from Panama City Beach to South Carolina by plane, bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Greenville–Spartanburg International Airport (GSP)plane plane ECP - GSP
    4h 7m
    $164–589

  2. Drive 447.2 mi

    cheapest
    1. Drive from Panama City Beach to Charlestoncar car 447.2 mi
    9h 4m
    $82–118

  3. Bus, train

    1. Take the bus from Panama City Beach Bus Station to Tallahasseebus bus
    2. Take the bus from Tallahassee to Jacksonvillebus bus
    3. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    13h 18m
    $155–304

  4. Fly Northwest Florida Beaches International Airport to Charlotte Douglas International Airport, taxi

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Charlotte Douglas International Airport (CLT)plane plane ECP - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    2h 47m
    $214–664

  5. Fly Northwest Florida Beaches International Airport to Charleston International Airport

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Charleston International Airport (CHS)plane plane ECP - CHS
    4h 47m
    $121–446

  6. Fly Northwest Florida Beaches International Airport to Columbia

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Columbia (CAE)plane plane ECP - CAE
    5h 47m
    $111–406

  7. Drive to Destin–Fort Walton Beach Airport, fly to Charlotte Douglas International Airport, taxi

    1. Drive from Panama City Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Charlotte Douglas International Airport (CLT)plane plane VPS - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    3h 45m
    $176–616

  8. Bus, train, taxi

    1. Take the bus from Panama City Beach Bus Station to Jacksonvillebus bus
    2. Take the train from Jacksonville to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    4. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    5. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    17h 27m

Northwest Florida Beaches International Airport (ECP) to Greenville–Spartanburg International Airport (GSP) flights

Calendar74Weekly Planes
Duration4h 25mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Panama City Beach to South Carolina.ExpandLaunch map view
  • Distance: 407 mi
  • Duration: 4h 7m

What companies run services between Panama City Beach, FL, USA and South Carolina, USA?

Delta, Southwest Airlines, and two other airlines fly from Northwest Florida Beaches International Airport (ECP) to Greenville–Spartanburg International Airport (GSP) every 2 hours.

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