There are 5 ways to get from Panama City to Fort Myers by plane, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Northwest Florida Beaches International Airport to Ft. Myers
best- Fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW)plane ECP - RSW
6h 29m$153–532Drive 456 mi
cheapest- Drive from Panama City to Fort Myerscar 456 mi
8h 35m$84–121Drive, bus
- Drive from Front Beach Rd. & Back Beach Rd. to Crestviewcar
- Take the bus from Crestview to Fort Myersbus Houston
14h 45m$114–150Drive to Destin–Fort Walton Beach Airport, fly to Ft. Myers
- Drive from Panama City to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Ft. Myers (RSW)plane VPS - RSW
7h 38m$100–473Fly Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport, bus
- Fly from Northwest Florida Beaches International Airport (ECP) to Sarasota–Bradenton International Airport (SRQ)plane ECP - SRQ
- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus
7h 55m$177–698
Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW) flights
Questions & Answers
The cheapest way to get from Panama City to Fort Myers is to drive which costs $80 - $120 and takes 8h 35m.
The fastest way to get from Panama City to Fort Myers is to fly which takes 6h 29m and costs $150 - $550.
The distance between Panama City and Fort Myers is 401 miles. The road distance is 458.7 miles.
It takes approximately 6h 29m to get from Panama City to Fort Myers, including transfers.
Fort Myers is 1h ahead of Panama City. It is currently 10:26 PM in Panama City and 11:26 PM in Fort Myers.
Yes, the driving distance between Panama City to Fort Myers is 459 miles. It takes approximately 8h 35m to drive from Panama City to Fort Myers.
There are 2658+ hotels available in Fort Myers.
What companies run services between Panama City, FL, USA and Fort Myers, FL, USA?
Delta, American Airlines, and two other airlines fly from Northwest Florida Beaches International Airport (ECP) to Ft. Myers (RSW) every 3 hours.
- Website
- delta.com
Flights from Northwest Florida Beaches International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $85–450
Flights from Destin–Fort Walton Beach Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $85–450
Flights from Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Northwest Florida Beaches International Airport to Ft. Myers via Nashville
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $110–550
Flights from Northwest Florida Beaches International Airport to Ft. Myers via St. Louis
- Ave. Duration
- 5h 46m
- When
- Saturday and Sunday
- Estimated price
- $150–650
Flights from Destin–Fort Walton Beach Airport to Ft. Myers via Nashville
- Ave. Duration
- 5h 33m
- When
- Saturday to Wednesday
- Estimated price
- $110–550
Flights from Destin–Fort Walton Beach Airport to Ft. Myers via St. Louis
- Ave. Duration
- 7h 50m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $140–650
Flights from Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport via Nashville
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $140–700
Flights from Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport via St. Louis
- Ave. Duration
- 8h 20m
- When
- Saturday
- Estimated price
- $190–850
- Website
- aa.com
Flights from Northwest Florida Beaches International Airport to Ft. Myers via Charlotte
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $100–550
Flights from Destin–Fort Walton Beach Airport to Ft. Myers via Charlotte
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $110–550
Flights from Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 5h 11m
- When
- Sunday
- Estimated price
- $130–700
- Website
- united.com
Flights from Northwest Florida Beaches International Airport to Ft. Myers via Houston
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $130–600
Flights from Northwest Florida Beaches International Airport to Sarasota–Bradenton International Airport via Houston
- Ave. Duration
- 8h 5m
- When
- Saturday
- Estimated price
- $170–800
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Crestview to Fort Myers
- Ave. Duration
- 10h 21m
- Frequency
- Once daily
- Estimated price
- $100–130
- Schedules at
- Omnibus Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
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