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How to get fromPanama City to Missouriby plane or car

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There are 7 ways to get from Panama City to Missouri by plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL)plane plane ECP - STL
    3h
    $163–630

  2. Drive to Destin–Fort Walton Beach Airport, fly to Springfield-Branson National Airport

    cheapest
    1. Drive from Panama City to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Springfield-Branson National Airport (SGF)plane plane VPS - SGF
    3h 51m
    $93–408

  3. Drive 935.8 mi

    1. Drive from Panama City to Kansas Citycar car 935.8 mi
    17h 5m
    $171–247

  4. Fly Northwest Florida Beaches International Airport to Kansas City

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Kansas City (MCI)plane plane ECP - MCI
    4h 23m
    $185–727

  5. Drive to Destin–Fort Walton Beach Airport, fly to Lambert–St. Louis International Airport

    1. Drive from Panama City to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Lambert–St. Louis International Airport (STL)plane plane VPS - STL
    4h 10m
    $110–571

  6. Drive to Pensacola International Airport, fly to Lambert–St. Louis International Airport

    1. Drive from Panama City to Pensacola-Airport-PNScar car
    2. Fly from Pensacola International Airport (PNS) to Lambert–St. Louis International Airport (STL)plane plane PNS - STL
    5h 2m
    $107–501

  7. Drive to Destin–Fort Walton Beach Airport, fly to Midamerica St. Louis Airport

    1. Drive from Panama City to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Midamerica St. Louis Airport (BLV)plane plane VPS - BLV
    4h 31m
    $103–420

Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL) flights

Calendar29Weekly Planes
Duration2h 53mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Missouri.ExpandLaunch map view
  • Distance: 671.4 mi
  • Duration: 3h

What companies run services between Panama City, FL, USA and Missouri, USA?

Southwest Airlines and Delta fly from Northwest Florida Beaches International Airport (ECP) to Lambert–St. Louis International Airport (STL) 4 times a day.

Airlines

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