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How to get fromPanama City to Niagara Fallsby plane, bus, car, or train

Find Transport to Niagara Falls

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There are 6 ways to get from Panama City to Niagara Falls by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Buffalo Niagara International Airport, bus

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF)plane plane ECP - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    6h 27m
    $199–785

  2. Drive to Destin–Fort Walton Beach Airport, fly to Buffalo Niagara International Airport, bus

    cheapest
    1. Drive from Panama City to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Buffalo Niagara International Airport (BUF)plane plane VPS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    7h 38m
    $156–726

  3. Drive 1,173.5 mi

    1. Drive from Panama City to Niagara Fallscar car 1,173.5 mi
    20h 27m
    $215–310

  4. Fly Northwest Florida Beaches International Airport to Toronto Pearson International Airport, bus

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Toronto Pearson International Airport (YYZ)plane plane ECP - YYZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    7h 58m
    $158–541

  5. Fly Northwest Florida Beaches International Airport to Rochester, train

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Rochester (ROC)plane plane ECP - ROC
    2. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    8h 20m
    $268–1,069

  6. Drive to Tallahassee, fly to Buffalo Niagara International Airport, bus

    1. Drive from Panama City to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Buffalo Niagara International Airport (BUF)plane plane TLH - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 20m
    $171–783

Northwest Florida Beaches International Airport (ECP) to Buffalo Niagara International Airport (BUF) flights

Calendar58Weekly Planes
Duration5h 59mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Niagara Falls.ExpandLaunch map view
  • Distance: 1,006.4 mi
  • Duration: 6h 27m

What companies run services between Panama City, FL, USA and Niagara Falls, NY, USA?

There is no direct connection from Panama City to Niagara Falls. However, you can take the taxi to Northwest Florida Beaches International Airport (ECP) airport, fly to Buffalo Niagara International Airport (BUF), walk to Buffalo Niagara International Airport, then take the bus to Niagara Falls USA. Alternatively, you can drive from Panama City to Niagara Falls in around 20h 27m.

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