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How to get fromPanama City to Sumterby plane, bus, or car

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There are 8 ways to get from Panama City to Sumter by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Northwest Florida Beaches International Airport to Florence Regional Airport, bus

    best
    1. Fly from Northwest Florida Beaches International Airport (ECP) to Florence Regional Airport (FLO)plane plane ECP - FLO
    2. Take the bus from Florence Bus Station to Sumter Bus Stopbus bus
    6h 44m
    $142–454

  2. Drive 476.2 mi

    cheapest
    1. Drive from Panama City to Sumtercar car 476.2 mi
    9h 21m
    $87–126

  3. Drive, bus

    1. Drive from Front Beach Rd. & Back Beach Rd. to Crestviewcar car
    2. Take the bus from Crestview to Tallahasseebus bus
    3. Take the bus from Tallahassee to Jacksonvillebus bus
    4. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    18h 49m
    $136–232

  4. Fly Northwest Florida Beaches International Airport to Columbia, bus

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Columbia (CAE)plane plane ECP - CAE
    2. Take the bus from Laurel Sumter East to James E Clyburn Intermodal Transportation Centerbus bus
    8h 24m
    $209–931

  5. Fly Northwest Florida Beaches International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Charlotte Douglas International Airport (CLT)plane plane ECP - CLT
    2. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    6h 41m
    $170–613

  6. Drive to Destin–Fort Walton Beach Airport, fly to Charlotte Douglas International Airport, bus

    1. Drive from Panama City to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Charlotte Douglas International Airport (CLT)plane plane VPS - CLT
    3. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    7h 47m
    $117–554

  7. Drive to Tallahassee, fly to Charlotte Douglas International Airport, bus

    1. Drive from Panama City to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Charlotte Douglas International Airport (CLT)plane plane TLH - CLT
    3. Take the bus from Charlotte Bus Station to Sumter Bus Stopbus bus
    8h 10m
    $127–611

  8. Fly Northwest Florida Beaches International Airport to Charleston International Airport, bus

    1. Fly from Northwest Florida Beaches International Airport (ECP) to Charleston International Airport (CHS)plane plane ECP - CHS
    2. Take the bus from Charleston Bus Station to Sumter Bus Stopbus bus
    10h 52m
    $153–491

Northwest Florida Beaches International Airport (ECP) to Florence Regional Airport (FLO) flights

Calendar15Weekly Planes
Duration6h 7mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Sumter.ExpandLaunch map view
  • Distance: 507.7 mi
  • Duration: 6h 44m

What companies run services between Panama City, FL, USA and Sumter, SC, USA?

There is no direct connection from Panama City to Sumter. However, you can take the taxi to Northwest Florida Beaches International Airport (ECP) airport, fly to Florence Regional Airport (FLO), take the taxi to Florence Bus Station, then take the bus to Sumter Bus Stop. Alternatively, you can take a bus from 11th St. & Harrison Ave. to Sumter Bus Stop via Gulf Coast State College, Front Beach Rd. & Back Beach Rd., Crestview, Tallahassee, N Monroe Street and Silver Slipper Lane, Tallahassee, and Jacksonville in around 18h 49m.

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