There are 4 ways to get from Panama City to Amazon rainforest by plane, car, ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Tocumen International Airport
best- Fly from Tocumen International Airport (PTY) to Manaus (MAO)plane PTY - MAO
6h 33mR$1,440–4,055Fly from Panama Pacific International Airport
cheapest- Fly from Panama Pacific International Airport (BLB) to Manaus (MAO)plane BLB - MAO
8h 24mR$983–3,764Drive, ferry, bus
- Drive from Panama City to Portobelocar
- Take the ferry from Portobelo to Cartagenaferry
- Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
- Take the bus from Terminal Cúcuta to Terminal San Cristóbalbus
- Take the bus from Terminal Expresos Los Llanos San Cristobal to Puerto La Cruzbus
- Take the bus from Puerto la Cruz to Manausbus
10d 18hR$5,025–5,447Drive, ferry, bus via Mérida
- Drive from Panama City to Portobelocar
- Take the ferry from Portobelo to Cartagenaferry
- Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
- Take the bus from Ureña to Terminal Jose Antonio Paredesbus
- Take the bus from Terminal Jose Antonio Paredes to Puerto La Cruzbus
- Take the bus from Puerto la Cruz to Manausbus
11d 7hR$5,023–5,509
Tocumen International Airport (PTY) to Manaus (MAO) flights
Questions & Answers
The cheapest way to get from Panama City to Amazon rainforest is to fly which costs R$ 950 - R$ 3800 and takes 8h 24m.
The fastest way to get from Panama City to Amazon rainforest is to fly which takes 6h 33m and costs R$ 1400 - R$ 4100.
The distance between Panama City and Amazon rainforest is 2565 km.
It takes approximately 6h 33m to get from Panama City to Amazon rainforest, including transfers.
There are 654+ hotels available in Amazon rainforest.
What companies run services between Panama City, Panama and Amazon rainforest, Brazil?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Manaus (MAO) twice daily.
- Website
- avianca.com
Flights from Tocumen International Airport to Manaus via Bogota
- Ave. Duration
- 8h 10m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- R$1,200–3,400
Flights from Panama Pacific International Airport to Manaus via Medellin Jose Marie Cordova, Bogota
- Ave. Duration
- 7h 59m
- When
- Friday
- Estimated price
- R$1,300–5,500
Flights from Panama Pacific International Airport to Manaus via Monteria, Bogota
- Ave. Duration
- 13h 35m
- When
- Sunday
- Estimated price
- R$1,400–5,500
Flights from Panama Pacific International Airport to Manaus via Barranquilla, Bogota
- Ave. Duration
- 15h 16m
- When
- Wednesday
- Estimated price
- R$1,400–5,500
Flights from Panama Pacific International Airport to Manaus via Cartagena, Bogota
- Ave. Duration
- 15h 22m
- When
- Sunday
- Estimated price
- R$1,400–5,500
Flights from Panama Pacific International Airport to Manaus via Cali, Bogota
- Ave. Duration
- 15h 24m
- When
- Wednesday and Friday
- Estimated price
- R$1,400–5,500
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal de Transporte de Cartagena to Terminal Cúcuta
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- R$250–340
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- R$250–340
Bus from Terminal de Transporte de Cartagena to Terminal Cúcuta
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- R$250–340
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- R$250–340
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Getting to Rome from the airport, Travelling to the US: What do I need to know?, and How to get from Heathrow Airport into central London - to help you get the most out of your next trip.