How to get fromPanama City to Amazon rainforestby plane, car, ferry, or bus

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There are 4 ways to get from Panama City to Amazon rainforest by plane, car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Tocumen International Airport
best
1. Fly from Tocumen International Airport (PTY) to Manaus (MAO)plane PTY - MAO
6h 34m
R$1,442–4,157
Fly from Panama Pacific International Airport
cheapest
1. Fly from Panama Pacific International Airport (BLB) to Manaus (MAO)plane BLB - MAO
8h 24m
R$1,084–3,865
Drive, ferry, bus
1. Drive from Panama City to Portobelocar
2. Take the ferry from Portobelo to Cartagenaferry
3. Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
4. Take the bus from Terminal Cúcuta to Terminal San Cristóbalbus
5. Take the bus from Terminal Expresos Los Llanos San Cristobal to Puerto La Cruzbus
6. Take the bus from Puerto la Cruz to Manausbus
10d 18h
R$5,047–5,469
Drive, ferry, bus via Mérida
1. Drive from Panama City to Portobelocar
2. Take the ferry from Portobelo to Cartagenaferry
3. Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
4. Take the bus from Ureña to Terminal Jose Antonio Paredesbus
5. Take the bus from Terminal Jose Antonio Paredes to Puerto La Cruzbus
6. Take the bus from Puerto la Cruz to Manausbus
11d 7h
R$5,045–5,531

Tocumen International Airport (PTY) to Manaus (MAO) flights

11Weekly Planes

6h 45mAverage Duration

R$697Cheapest Price

Questions & Answers

Map of how to get from Panama City to Amazon rainforest.

Launch map view

Distance: 2,565 km
Duration: 6h 34m

What companies run services between Panama City, Panama and Amazon rainforest, Brazil?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Manaus (MAO) twice daily.

Airlines

Bus operators

Ferry operators

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Manaus(opens in a new window), Brazil(opens in a new window)

Manaus is the capital and largest city of the Brazilian state of Amazonas. It is the seventh-largest city in Brazil, with an estimated 2020 population of 2,219,580 distributed over a land area of about. Located at the east centre of the state, the city is the centre of the Manaus metropolitan area and the largest metropolitan area in the North Region of Brazil by urban landmass. It is situated near the confluence of the Negro and Amazon rivers. It is one of the two cities in the Amazon Rainforest with a population of over 1 million people, alongside Belém.

Places to stay in Manaus

Manaus Hotéis Millennium(Opens in a new window)

8.5Very Good

Da Vinci Hotel & Conventions - by Easy Hotéis(Opens in a new window)

8.0Good

Space Residence(Opens in a new window)

8.6Fabulous

Express Vieiralves(Opens in a new window)

8.2Very Good

Rome2Rio makes travelling from Panama City to Amazon rainforest easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Panama City to Amazon rainforest right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.