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How to get fromPanama City to Amazon rainforestby plane, car, ferry, or bus

Find Transport to Amazon rainforest

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There are 4 ways to get from Panama City to Amazon rainforest by plane, car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tocumen International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Manaus (MAO)plane plane PTY - MAO
    6h 33m
    R$1,439–4,154

  2. Fly from Panama Pacific International Airport

    cheapest
    1. Fly from Panama Pacific International Airport (BLB) to Manaus (MAO)plane plane BLB - MAO
    7h 31m
    R$932–3,663

  3. Drive, ferry, bus

    1. Drive from Panama City to Portobelocar car
    2. Take the ferry from Portobelo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus bus
    4. Take the bus from Terminal Cúcuta to Terminal San Cristóbalbus bus
    5. Take the bus from Terminal Expresos Los Llanos San Cristobal to Puerto La Cruzbus bus
    6. Take the bus from Puerto la Cruz to Manausbus bus
    10d 18h
    R$4,982–5,403

  4. Drive, ferry, bus via Mérida

    1. Drive from Panama City to Portobelocar car
    2. Take the ferry from Portobelo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus bus
    4. Take the bus from Ureña to Terminal Jose Antonio Paredesbus bus
    5. Take the bus from Terminal Jose Antonio Paredes to Puerto La Cruzbus bus
    6. Take the bus from Puerto la Cruz to Manausbus bus
    11d 7h
    R$4,980–5,465

Tocumen International Airport (PTY) to Manaus (MAO) flights

Calendar11Weekly Planes
Duration6h 44mAverage Duration
TicketR$649Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Panama City to Amazon rainforest.ExpandLaunch map view
  • Distance: 2,565 km
  • Duration: 6h 33m

What companies run services between Panama City, Panama and Amazon rainforest, Brazil?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Manaus (MAO) twice daily.

Airlines
Bus operators
Ferry operators

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