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How to get fromPanama City to Buffaloby plane, car, bus, taxi, or train

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There are 6 ways to get from Panama City to Buffalo by plane, car, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF)plane plane PTY - BUF
    10h 24m
    $343–1,266

  2. Fly to Bradford Regional Airport, taxi, bus

    cheapest
    1. Fly from Tocumen International Airport (PTY) to Bradford Regional Airport (BFD)plane plane PTY - BFD
    2. Take the taxi from Bradford Regional Airport (BFD) to Salamancataxi taxi
    3. Take the bus from Salamanca to Buffalobus bus
    15h 44m
    $242–854

  3. Drive  4,140.4 mi

    1. Drive from Panama City to Buffalocar car 4,140.4 mi
    3d 13h
    $792–1,144

  4. Fly to Rochester, bus

    1. Fly from Tocumen International Airport (PTY) to Rochester (ROC)plane plane PTY - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    11h 42m
    $447–1,681

  5. Fly to Toronto Pearson International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Toronto Pearson International Airport (YYZ)plane plane PTY - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    12h 5m
    $383–862

  6. Fly to Toronto Island Airport, bus, train

    1. Fly from Tocumen International Airport (PTY) to Toronto Island Airport (YTZ)plane plane PTY - YTZ
    2. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    3. Take the train from Niagara Falls Amtrak Station to Buffalotrain train
    15h 20m
    $535–1,306

Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF) flights

Calendar26Weekly Planes
Duration8h 34mAverage Duration
Ticket$300Cheapest Price
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Comparing Your Travel Options

Map of how to get from Panama City to Buffalo.ExpandLaunch map view
  • Distance: 2,365.1 mi
  • Duration: 10h 24m

What companies run services between Panama City, Panama and Buffalo, NY, USA?

American Airlines, Delta, and four other airlines fly from Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF) 4 times a day.

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