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How to get fromPanama City to Buffaloby plane, car, bus, or train

Find Transport to Buffalo

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There are 5 ways to get from Panama City to Buffalo by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF)plane plane PTY - BUF
    10h 44m
    $303–1,166

  2. Drive  4,139 mi

    1. Drive from Panama City to Buffalocar car 4,139 mi
    3d 13h
    $912–1,317

  3. Fly to Toronto Pearson International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Toronto Pearson International Airport (YYZ)plane plane PTY - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    12h 7m
    $362–961

  4. Fly to Rochester, bus

    1. Fly from Tocumen International Airport (PTY) to Rochester (ROC)plane plane PTY - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    13h 2m
    $417–1,579

  5. Fly to Toronto Island Airport, bus, train

    1. Fly from Tocumen International Airport (PTY) to Toronto Island Airport (YTZ)plane plane PTY - YTZ
    2. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    3. Take the train from Niagara Falls Amtrak Station to Buffalotrain train
    15h 14m
    $531–1,333

Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF) flights

Calendar34Weekly Planes
Duration7h 59mAverage Duration
Ticket$260Cheapest Price
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Comparing Your Travel Options

Map of how to get from Panama City to Buffalo.ExpandLaunch map view
  • Distance: 2,365.1 mi
  • Duration: 10h 44m

What companies run services between Panama City, Panama and Buffalo, NY, USA?

American Airlines, Delta, and five other airlines fly from Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF) 5 times a day.

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