Rome2Rio

How to get fromPanama City to Buffaloby plane, car, bus, or train

Find Transport to Buffalo

See all options

There are 5 ways to get from Panama City to Buffalo by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF)plane plane PTY - BUF
    10h 45m
    $299–1,141

  2. Drive  4,139 mi

    1. Drive from Panama City to Buffalocar car 4,139 mi
    3d 13h
    $912–1,317

  3. Fly to Toronto Pearson International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Toronto Pearson International Airport (YYZ)plane plane PTY - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    12h 7m
    $362–960

  4. Fly to Rochester, bus

    1. Fly from Tocumen International Airport (PTY) to Rochester (ROC)plane plane PTY - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    12h 17m
    $407–1,479

  5. Fly to Toronto Island Airport, bus, train

    1. Fly from Tocumen International Airport (PTY) to Toronto Island Airport (YTZ)plane plane PTY - YTZ
    2. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    3. Take the train from Niagara Falls Amtrak Station to Buffalotrain train
    14h 59m
    $531–1,233

Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF) flights

Calendar41Weekly Planes
Duration8h 1mAverage Duration
Ticket$266Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Panama City to Buffalo.ExpandLaunch map view
  • Distance: 2,365.2 mi
  • Duration: 10h 45m

What companies run services between Panama City, Panama and Buffalo, NY, USA?

Copa Airlines, United Airlines, and five other airlines fly from Tocumen International Airport (PTY) to Buffalo Niagara International Airport (BUF) every 4 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound