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How to get fromPanama City to Cartagenaby plane, bus, or train

Find Transport to Cartagena

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There are 7 ways to get from Panama City to Cartagena by plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Tocumen International Airport to Alicante-Elche Airport, bus

    best
    1. Fly from Tocumen International Airport (PTY) to Alicante-Elche Airport (ALC)plane plane PTY - ALC
    2. Take the bus from Alicante Aeropuerto to Estación de Autobuses de Murciabus bus
    3. Take the bus from Estación de Autobuses de Murcia to Estación de Autobuses de Cartagenabus bus
    18h 48m
    €403–1,149

  2. Fly Tocumen International Airport to Almería Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Almería Airport (LEI)plane plane PTY - LEI
    2. Take the bus from Almería to Cartagenabus bus
    20h 20m
    €601–1,670

  3. Fly Tocumen International Airport to Valencia Airport, train

    1. Fly from Tocumen International Airport (PTY) to Valencia Airport (VLC)plane plane PTY - VLC
    2. Take the train from Estació del Nord to Alacant/Alicante Terminaltrain train
    3. Take the train from Alacant/Alicante Terminal to Murcia Del Carmentrain train
    4. Take the train from Murcia Del Carmen to Cartagenatrain train
    21h 41m
    €574–1,007

  4. Fly Tocumen International Airport to Adolfo Suárez Madrid–Barajas Airport, train

    1. Fly from Tocumen International Airport (PTY) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PTY - MAD
    2. Take the train from Madrid Chamartín to Murcia Del Carmentrain train
    3. Take the train from Murcia Del Carmen to Cartagenatrain train
    18h 13m
    €457–989

  5. Fly Panama Pacific International Airport to Alicante-Elche Airport, bus

    1. Fly from Panama Pacific International Airport (BLB) to Alicante-Elche Airport (ALC)plane plane BLB - ALC
    2. Take the bus from Alicante Aeropuerto to Estación de Autobuses de Murciabus bus
    3. Take the bus from Estación de Autobuses de Murcia to Estación de Autobuses de Cartagenabus bus
    18h
    €405–1,133

  6. Fly Tocumen International Airport to Federico García Lorca Granada-Jaén Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Federico García Lorca Granada-Jaén Airport (GRX)plane plane PTY - GRX
    2. Take the bus from Granada Estación de Autobuses to Cartagenabus bus
    22h 29m
    €511–1,376

  7. Fly Panama Pacific International Airport to Adolfo Suárez Madrid–Barajas Airport, train

    1. Fly from Panama Pacific International Airport (BLB) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane BLB - MAD
    2. Take the train from Madrid Chamartín to Murcia Del Carmentrain train
    3. Take the train from Murcia Del Carmen to Cartagenatrain train
    18h 8m
    €479–1,073

Tocumen International Airport (PTY) to Alicante-Elche Airport (ALC) flights

Calendar23Weekly Planes
Duration15h 57mAverage Duration
Ticket€346Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Cartagena.ExpandLaunch map view
  • Distance: 8,561.9 km
  • Duration: 18h 48m

What companies run services between Panama City, Panama and Cartagena, Spain?

There is no direct connection from Panama City to Cartagena. However, you can take the shuttle to Aeropuerto Internacional de Tocumen, walk to Tocumen International Airport (PTY) airport, fly to Alicante-Elche Airport (ALC), walk to Alicante Aeropuerto, take the bus to Estación de Autobuses de Murcia, then take the bus to Estación de Autobuses de Cartagena. Alternatively, you can take the shuttle to Aeropuerto Internacional de Tocumen, walk to Tocumen International Airport (PTY) airport, fly to Almería Airport (LEI), walk to Aeropuerto Almeria-Al, take the bus to Gregorio Marañon. 45-Al, walk to Almería, then take the bus to Cartagena.

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