There are 5 ways to get from Panama City to Comayagua by plane, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Tocumen International Airport (PTY) to Palmerola Airport (XPL)plane PTY - XPL
4h 25m$263–795Bus
cheapest- Take the bus from Terminal de Albrook to Terminal Tica Busbus
- Take the bus from Terminal NicaBus to Chinandegabus
- Take the bus from Chinandega to Cholutecabus Mga
- Take the bus from Choluteca to Tegucigalpabus
- Take the bus from Toncontín Airport to Comayaguabus
38h 48m$132–180Bus, drive, taxi
- Take the bus from Terminal de Albrook to Terminal Tica Busbus
- Take the bus from Terminal NicaBus to Managuabus
- Take the bus from Managua to Ocotalbus
- Drive from Ocotal to Danlícar
- Take the bus from Danlí to Cantarranasbus
- Take the taxi from Cantarranas to Toncontín Airporttaxi
- Take the bus from Toncontín Airport to Comayaguabus
34h 5mDrive 1,558.4 km
- Drive from Panama City to Comayaguacar 1,558.4 km
23h 37m$215–310Bus via Managua
- Take the bus from Terminal de Albrook to Terminal Tica Busbus
- Take the bus from Terminal Atlántico Norte to Terminal Managua - CCAbus Sjo
- Take the bus from Terminal Managua - CCA to Cholutecabus Mga
- Take the bus from Choluteca to Tegucigalpabus
- Take the bus from Toncontín Airport to Comayaguabus
42h 40m$132–192
Tocumen International Airport (PTY) to Palmerola Airport (XPL) flights
Comparing Your Travel Options
The cheapest way to get from Panama City to Comayagua is to bus which costs $130 - $180 and takes 38h 48m.
The fastest way to get from Panama City to Comayagua is to fly which takes 4h 25m and costs $260 - $800.
No, there is no direct bus from Panama City to Comayagua. However, there are services departing from Terminal de Albrook and arriving at Comayagua via Terminal NicaBus, Chinandega, Choluteca and Toncontín Airport. The journey, including transfers, takes approximately 38h 48m.
The distance between Panama City and Comayagua is 1106 km. The road distance is 1558.4 km.
The best way to get from Panama City to Comayagua without a car is to bus which takes 38h 48m and costs $130 - $180.
It takes approximately 4h 25m to get from Panama City to Comayagua, including transfers.
Panama City to Comayagua bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), depart from Terminal de Albrook station.
The best way to get from Panama City to Comayagua is to fly which takes 4h 25m and costs $260 - $800. Alternatively, you can bus, which costs $130 - $180 and takes 38h 48m.
Panama City to Comayagua bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), arrive at Terminal Tica Bus station.
Comayagua is 1h behind Panama City. It is currently 4:12 AM in Panama City and 3:12 AM in Comayagua.
What companies run services between Panama City, Panama and Comayagua, Honduras?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Palmerola Airport (XPL) 4 times a day. Alternatively, you can take a bus from Terminal de Albrook to Comayagua via Terminal Tica Bus, Terminal NicaBus, Chinandega, Choluteca, Choluteca, Tegucigalpa, and Toncontín Airport in around 38h 48m.
- Website
- copaair.com
Flights from Tocumen International Airport to Palmerola Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $85–490
- Website
- avianca.com
Flights from Tocumen International Airport to Palmerola Airport via San Salvador
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $220–750
Bus from Terminal de Albrook to Terminal Tica Bus
- Ave. Duration
- 15h 30m
- Frequency
- 4 times a day
- Estimated price
- $58–90
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $60–90
Bus from Terminal de Albrook to Terminal Tica Bus
- Ave. Duration
- 15h 30m
- Frequency
- 4 times a day
- Estimated price
- $58–90
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $60–90
Bus from Chinandega to Choluteca
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $8–13
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $8–13
Bus from Terminal de Albrook to Terminal Tica Bus
- Ave. Duration
- 15h 30m
- Frequency
- 4 times a day
- Estimated price
- $58–90
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $60–90
Bus from Terminal Atlántico Norte to Terminal Managua - CCA
- Ave. Duration
- 12h
- Frequency
- 5 times a day
- Estimated price
- $30–50
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $30–50
Bus from Terminal Managua - CCA to Choluteca
- Ave. Duration
- 7h 30m
- Frequency
- 3 times a week
- Estimated price
- $18–25
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $18–25
- Phone
- +505 2222 2276
- [email protected]
- Website
- Nica Bus
Bus from Terminal NicaBus to Managua
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $37–38
- Website
- Nica Bus
Bus from Terminal NicaBus to Chinandega
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $40–50
- Website
- Nica Bus
- Phone
- +505 22330961
- Website
- COTRAN R.L.
Bus from Managua to Ocotal
- Ave. Duration
- 2h 40m
- Frequency
- Every 3 hours
- Estimated price
- $4–7
- Schedules at
- COTRAN R.L.
Bus from Danlí to Cantarranas
- Ave. Duration
- 1h 8m
- Frequency
- 3 times a day
- Schedules at
- Travel with Hello - Honduras public transport
- Phone
- +504 9394 4107
- [email protected]
- Website
- Transporte Ejecutivo 5 Estrellas
Bus from Toncontín Airport to Comayagua
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- Transporte Ejecutivo 5 Estrellas
Bus from Toncontín Airport to Comayagua
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- Transporte Ejecutivo 5 Estrellas
Bus from Toncontín Airport to Comayagua
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- Transporte Ejecutivo 5 Estrellas
- Phone
- +504 782 0841
- Website
- Mi Esperanza del Sur
Bus from Choluteca to Tegucigalpa
- Ave. Duration
- 3h 14m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- Mi Esperanza del Sur
Bus from Choluteca to Tegucigalpa
- Ave. Duration
- 3h 14m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- Mi Esperanza del Sur
- Ave. Duration
- 54 min
- Estimated price
- $35–50
Honduras City Tours Taxi
- Phone
- +504 2234-0344
- Website
- citytourstaxi.com
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Booking & Getting There
Yes, the driving distance between Panama City to Comayagua is 1558 km. It takes approximately 23h 37m to drive from Panama City to Comayagua.
There are 44+ hotels available in Comayagua.








