There are 5 ways to get from Panama City to Comayagua by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Tocumen International Airport (PTY) to Palmerola Airport (XPL)plane PTY - XPL
4h 30m$233–455Bus via Paso Canoas
cheapest- Take the bus from Albrook - Panama to Fronterabus
- Take the bus from Paso Canoas to San Josébus
- Take the bus from Terminal TransNica to Managuabus
- Take the bus from Terminal Tica Bus Managua to Terminal Tica Bus Tegucigalpabus
- Take the bus from Toncontín Airport to Comayaguabus
41h 11m$108–145Bus
- Take the bus from Terminal Albrook to Terminal Tica Busbus
- Take the bus from Terminal NicaBus to Managuabus
- Take the bus from Terminal Tica Bus Managua to Terminal Tica Bus Tegucigalpabus
- Take the bus from Toncontín Airport to Comayaguabus
38h 44m$131–174Drive 1,558.4 km
- Drive from Panama City to Comayaguacar 1,558.4 km
23h 37m$215–310Bus via Fernandez de Cordoba
- Take the bus from Terminal Albrook to Terminal Tica Busbus
- Take the bus from Terminal Tica Bus to Managuabus
- Take the bus from Terminal Tica Bus Managua to Terminal Tica Bus Tegucigalpabus
- Take the bus from Toncontín Airport to Comayaguabus
42h 39m$121–183
Tocumen International Airport (PTY) to Palmerola Airport (XPL) flights
Questions & Answers
The cheapest way to get from Panama City to Comayagua is to bus via Paso Canoas which costs $100 - $150 and takes 41h 11m.
The fastest way to get from Panama City to Comayagua is to fly which takes 4h 30m and costs $230 - $460.
No, there is no direct bus from Panama City to Comayagua. However, there are services departing from Terminal Albrook and arriving at Comayagua via Terminal NicaBus, Terminal Tica Bus Managua and Toncontín Airport. The journey, including transfers, takes approximately 38h 44m.
The distance between Panama City and Comayagua is 1106 km. The road distance is 1558.4 km.
The best way to get from Panama City to Comayagua without a car is to bus which takes 38h 44m and costs $130 - $180.
It takes approximately 4h 30m to get from Panama City to Comayagua, including transfers.
Panama City to Comayagua bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), depart from Terminal Albrook station.
The best way to get from Panama City to Comayagua is to fly which takes 4h 30m and costs $230 - $460. Alternatively, you can bus, which costs $130 - $180 and takes 38h 44m.
Panama City to Comayagua bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), arrive at Terminal Tica Bus station.
Comayagua is 1h behind Panama City. It is currently 6:09 PM in Panama City and 5:09 PM in Comayagua.
What companies run services between Panama City, Panama and Comayagua, Honduras?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Palmerola Airport (XPL) 4 times a day. Alternatively, you can take a bus from Terminal Albrook to Comayagua via Terminal Tica Bus, Terminal NicaBus, Managua, Terminal Tica Bus Managua, Tegucigalpa, and Toncontín Airport in around 38h 44m.
- Website
- copaair.com
Flights from Tocumen International Airport to Palmerola Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $70–370
- Website
- avianca.com
Flights from Tocumen International Airport to Palmerola Airport via San Salvador
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $190–410
- Phone
- +504 9919 5375
- Website
- cristobalcolon.com.gt
Bus from Terminal Albrook to Terminal Tica Bus
- Ave. Duration
- 15h 30m
- Frequency
- 4 times a day
- Estimated price
- $58–90
- Schedules at
- cristobalcolon.com.gt
- Road
- $60–90
Bus from Terminal Albrook to Terminal Tica Bus
- Ave. Duration
- 15h 30m
- Frequency
- 4 times a day
- Estimated price
- $58–90
- Schedules at
- cristobalcolon.com.gt
- Road
- $60–90
- Phone
- +52 962 625 2435
- [email protected]
- Website
- ticabus.com
Bus from Terminal Albrook to Terminal Tica Bus
- Ave. Duration
- 17h
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- https://www.ticabus.com/en/
Bus from Terminal Tica Bus Managua to Terminal Tica Bus Tegucigalpa
- Ave. Duration
- 11h
- Frequency
- Twice daily
- Estimated price
- $28–40
- Website
- https://www.ticabus.com/en/
Bus from Terminal Tica Bus Managua to Terminal Tica Bus Tegucigalpa
- Ave. Duration
- 11h
- Frequency
- Twice daily
- Estimated price
- $28–40
- Website
- https://www.ticabus.com/en/
Bus from Terminal Albrook to Terminal Tica Bus
- Ave. Duration
- 17h
- Frequency
- Once daily
- Estimated price
- $55–80
- Website
- https://www.ticabus.com/en/
Bus from Terminal Tica Bus to Managua
- Ave. Duration
- 11h
- Frequency
- 4 times a day
- Estimated price
- $30–45
- Website
- https://www.ticabus.com/en/
Bus from Terminal Tica Bus Managua to Terminal Tica Bus Tegucigalpa
- Ave. Duration
- 11h
- Frequency
- Twice daily
- Estimated price
- $28–40
- Website
- https://www.ticabus.com/en/
- Phone
- +505 2222 2276
- [email protected]
- Website
- nicabus.com.ni
Bus from Terminal NicaBus to Managua
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $37–38
- Website
- https://nicabus.com.ni/en/
- Website
- facebook.com
Bus from Toncontín Airport to Comayagua
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- facebook.com
Bus from Toncontín Airport to Comayagua
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- facebook.com
Bus from Toncontín Airport to Comayagua
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $8
- Schedules at
- facebook.com
- Phone
- +507 314 6886
- [email protected]
- Website
- facebook.com
Bus from Albrook - Panama to Frontera
- Ave. Duration
- 8h
- Frequency
- Every 2 hours
- Estimated price
- $20–23
- Schedules at
- facebook.com
- Phone
- +506 2221 4214
- [email protected]
- Website
- tracopacr.com
Bus from Paso Canoas to San José
- Ave. Duration
- 7h 7m
- Frequency
- Every 2 hours
- Estimated price
- $21–25
- Schedules at
- tracopacr.com
- Colectivo
- $21–25
- Phone
- +506 4404 0500
- [email protected]
- Website
- transnica.com
Bus from Terminal TransNica to Managua
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Schedules at
- transnica.com
- Book at
- ventas.transnica.com
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More Questions & Answers
Yes, the driving distance between Panama City to Comayagua is 1558 km. It takes approximately 23h 37m to drive from Panama City to Comayagua.
There are 50+ hotels available in Comayagua.












