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How to get fromPanama City to Fort Myersby plane, bus, or car

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There are 7 ways to get from Panama City to Fort Myers by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Miami International Airport, bus

    best
    1. Fly from Tocumen International Airport (PTY) to Miami International Airport (MIA)plane plane PTY - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    10h 7m
    $284–533

  2. Fly to Ft. Myers

    cheapest
    1. Fly from Tocumen International Airport (PTY) to Ft. Myers (RSW)plane plane PTY - RSW
    10h 8m
    $171–643

  3. Drive 3,748.7 mi

    1. Drive from Panama City to Fort Myerscar car 3,748.7 mi
    3d 6h
    $826–1,193

  4. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PTY - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    9h 6m
    $389–628

  5. Fly to Tampa, bus

    1. Fly from Tocumen International Airport (PTY) to Tampa (TPA)plane plane PTY - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    11h 1m
    $431–680

  6. Fly to Sarasota–Bradenton International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Sarasota–Bradenton International Airport (SRQ)plane plane PTY - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    11h 39m
    $211–761

  7. Fly to Orlando, bus

    1. Fly from Tocumen International Airport (PTY) to Orlando (MCO)plane plane PTY - MCO
    2. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    13h 21m
    $375–595

Tocumen International Airport (PTY) to Miami International Airport (MIA) flights

Calendar63Weekly Planes
Duration3h 47mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Fort Myers.ExpandLaunch map view
  • Distance: 1,332.2 mi
  • Duration: 10h 7m

What companies run services between Panama City, Panama and Fort Myers, FL, USA?

Delta, Copa Airlines, and Southwest Airlines fly from Tocumen International Airport (PTY) to Ft. Myers (RSW) twice daily.

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Bus operators

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