How to get fromPanama City to Medellínby plane, bus, or ferry

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There are 4 ways to get from Panama City to Medellín by plane, bus, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Panama Pacific International Airport
best
1. Fly from Panama Pacific International Airport (BLB) to Medellin Jose Marie Cordova (MDE)plane BLB - MDE
2h 17m
$147–250
Bus, Tour, ferry
1. Take the bus from Panama City to Cartíbus
2. Take the ferry from Cartí to Sapzurroferry
3. Take the ferry from Sapzurro to Necocliferry
4. Take the bus from Necoclí to Terminal del Nortebus
5d 17h
Fly from Tocumen International Airport
1. Fly from Tocumen International Airport (PTY) to Medellin Jose Marie Cordova (MDE)plane PTY - MDE
4h 40m
$253–468
Bus, Tour, ferry via Currulao
1. Take the bus from Panama City to Cartíbus
2. Take the ferry from Cartí to Sapzurroferry
3. Take the ferry from Sapzurro to Necocliferry
4. Take the bus from Necoclí to Currulaobus
5. Take the bus from Currulao to Terminal del Nortebus
5d 20h

Panama Pacific International Airport (BLB) to Medellin Jose Marie Cordova (MDE) flights

11Weekly Planes

1h 17mAverage Duration

$98Cheapest Price

Questions & Answers

Map of how to get from Panama City to Medellín.

Launch map view

Distance: 581.9 km
Duration: 2h 17m

What companies run services between Panama City, Panama and Medellín, Colombia?

AeroRepública flies from Panama Pacific International Airport (BLB) to Medellin Jose Marie Cordova (MDE) twice daily.

Airlines

Bus operators

Ferry operators

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Medellín(opens in a new window), Colombia(opens in a new window)

Medellín, officially the Special District of Science, Technology and Innovation of Medellín (Spanish: Distrito Especial de Ciencia, Tecnología e Innovación de Medellín), is the second-largest city in Colombia after Bogotá, and the capital of the department of Antioquia. It is located in the Aburrá Valley, a central region of the Andes Mountains, in northwestern South America. The city's population was 2,508,452 at the 2018 census. The metro area of Medellín is the second-largest urban agglomeration in Colombia in terms of population and economy, with more than 4 million people.

Places to stay in Medellín

Terra Biohotel(Opens in a new window)

8.6Fabulous

Rivière Boutique Hotel(Opens in a new window)

8.2Very Good

Casa Entera-Cerca a Mall La Central y Estación de Tranvía(Opens in a new window)

8.9Fabulous

Best Western Plus Hotel San Diego(Opens in a new window)

8.8Fabulous

Rome2Rio makes travelling from Panama City to Medellín easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Panama City to Medellín right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.