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How to get fromPanama City to Mexicaliby plane, bus, or car

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There are 6 ways to get from Panama City to Mexicali by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Rodolfo Sánchez Taboada International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to General Rodolfo Sánchez Taboada International Airport (MXL)plane plane PTY - MXL
    11h
    $5,598–17,448

  2. Bus

    cheapest
    1. Take the bus from Terminal Tica Bus Panamá to Terminal Tica Bus San Josébus bus
    2. Take the bus from Terminal Tica Bus to El Salvadorbus bus
    3. Take the bus from San Salvador to Tapachulabus bus
    4. Take the bus from Tapachula to Huixtlabus bus
    5. Take the bus from Huixtla to Mexicalibus bus
    5d 3h
    $4,621–7,105

  3. Bus via Mexico City

    1. Take the bus from Terminal Albrook to Terminal Tica Busbus bus
    2. Take the bus from Terminal Atlántico Norte to Terminal San Carlos - CCAbus bus
    3. Take the bus from San Salvador to Tapachulabus bus
    4. Take the bus from Tapachula to Politécnicobus bus
    5. Take the bus from Terminal Central de Autobuses del Norte to Mexicalibus bus
    4d 12h
    $6,700–12,723

  4. Drive 5,765.3 km

    1. Drive from Panama City to Mexicalicar car 5,765.3 km
    3d
    $13,454–19,433

  5. Fly to Tijuana International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to Tijuana International Airport (TIJ)plane plane PTY - TIJ
    2. Take the bus from Tijuana International Airport to Mexicalibus bus
    14h 20m
    $4,698–15,298

  6. Fly to San Diego International Airport, bus

    1. Fly from Tocumen International Airport (PTY) to San Diego International Airport (SAN)plane plane PTY - SAN
    2. Take the bus from Tijuana to Mexicalibus bus
    13h 35m
    $5,288–17,648

Tocumen International Airport (PTY) to General Rodolfo Sánchez Taboada International Airport (MXL) flights

Calendar37Weekly Planes
Duration11h 18mAverage Duration
Ticket$4,329Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Mexicali.ExpandLaunch map view
  • Distance: 4,563.1 km
  • Duration: 11h

What companies run services between Panama City, Panama and Mexicali, Mexico?

Copa Airlines, Volaris, and Aeroméxico fly from Tocumen International Airport (PTY) to General Rodolfo Sánchez Taboada International Airport (MXL) 5 times a day. Alternatively, you can take a bus from Terminal Albrook to Mexicali via Terminal Tica Bus, Terminal Atlántico Norte, Terminal San Carlos - CCA, San Salvador, Tapachula, Politécnico, Paradero Politécnico, Poniente 112, and Terminal Central de Autobuses del Norte in around 4d 12h.

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