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How to get fromPanama City to Mexico Cityby plane, bus, car, or shuttle

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There are 5 ways to get from Panama City to Mexico City by plane, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tocumen International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Benito Juárez International Airport (MEX)plane plane PTY - MEX
    6h 2m
    $4,547–9,647

  2. Fly from Panama Pacific International Airport

    cheapest
    1. Fly from Panama Pacific International Airport (BLB) to Benito Juárez International Airport (MEX)plane plane BLB - MEX
    7h 20m
    $2,792–10,345

  3. Bus

    1. Take the bus from Terminal Albrook to Terminal Tica Busbus bus
    2. Take the bus from San José to San Salvadorbus bus
    3. Take the bus from San Salvador to Panajachelbus bus
    4. Take the bus from Panajachel to Comitánbus bus
    5. Take the bus from Comitán to México Citybus bus
    2d 19h
    $4,374–5,291

  4. Drive 3,182.3 km

    1. Drive from Panama City to Mexico Citycar car 3,182.3 km
    44h 6m
    $7,417–10,714

  5. Bus, shuttle

    1. Take the bus from Terminal Tica Bus Panamá to Terminal Tica Bus San Josébus bus
    2. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus San Salvadorbus bus
    3. Take a shuttle bus from San Salvador to Antigua Guatemalashuttle bus
    4. Take the bus from Antigua Guatemala to Tapachulabus bus
    5. Take the bus from Tapachula to Terminal Central de Autobuses del Nortebus bus
    3d 12h
    $5,202–8,500

Tocumen International Airport (PTY) to Benito Juárez International Airport (MEX) flights

Calendar56Weekly Planes
Duration4h 5mAverage Duration
Ticket$1,983Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Mexico City.ExpandLaunch map view
  • Distance: 2,436.3 km
  • Duration: 6h 2m

What companies run services between Panama City, Panama and Mexico City, Mexico?

Aeroméxico, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Benito Juárez International Airport (MEX) every 4 hours. Alternatively, you can take a bus from Terminal Albrook to México City via Terminal Tica Bus, San José, San Salvador, Panajachel, and Comitán in around 2d 19h.

Airlines
Bus operators

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