There are 4 ways to get from Panama City to San Diego by plane, bus (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to San Diego International Airport
best- Fly from Tocumen International Airport (PTY) to San Diego International Airport (SAN)plane PTY - SAN
8h 53m$268–938Fly to Tijuana International Airport
cheapest- Fly from Tocumen International Airport (PTY) to Tijuana International Airport (TIJ)plane PTY - TIJ
13h 38m$251–912Bus
- Take the bus from Terminal Albrook to Terminal Tica Busbus
- Take the bus from Terminal NicaBus to Managuabus
- Take the bus from Managua to Los Angelesbus
- Take the bus from Los Angeles to San Diegobus
5d 12h$466–588Drive 3,701.4 mi
- Drive from Panama City to San Diegocar 3,701.4 mi
3d 2h$815–1,178
Tocumen International Airport (PTY) to San Diego International Airport (SAN) flights
Questions & Answers
The cheapest way to get from Panama City to San Diego is to bus which costs $460 - $600 and takes 5 days 12h.
The fastest way to get from Panama City to San Diego is to fly which takes 8h 53m and costs $260 - $950.
No, there is no direct bus from Panama City to San Diego. However, there are services departing from Terminal Albrook and arriving at San Diego via Terminal NicaBus, Managua, Olympic / Union and Los Angeles. The journey, including transfers, takes approximately 5 days 12h.
The distance between Panama City and San Diego is 2944 miles. The road distance is 3723 miles.
The best way to get from Panama City to San Diego without a car is to bus which takes 5 days 12h and costs $460 - $600.
It takes approximately 8h 53m to get from Panama City to San Diego, including transfers.
Panama City to San Diego bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), depart from Terminal Albrook station.
The best way to get from Panama City to San Diego is to fly which takes 8h 53m and costs $260 - $950. Alternatively, you can bus, which costs $460 - $600 and takes 5 days 12h.
Panama City to San Diego bus services, operated by Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter), arrive at Terminal Tica Bus station.
San Diego is 2h behind Panama City. It is currently 1:09 PM in Panama City and 11:09 AM in San Diego.
What companies run services between Panama City, Panama and San Diego, CA, USA?
Copa Airlines and United Airlines fly from Tocumen International Airport (PTY) to San Diego International Airport (SAN) 5 times a day. Alternatively, you can take a bus from Terminal Albrook to San Diego via Terminal Tica Bus, Terminal NicaBus, Managua, Los Angeles, Olympic / Union, Cesar E Chavez / Alameda, and Los Angeles in around 5d 12h.
- Website
- copaair.com
Flights from Tocumen International Airport to San Diego International Airport
- Ave. Duration
- 6h 29m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $230–900
Flights from Tocumen International Airport to San Diego International Airport via Los Angeles
- Ave. Duration
- 10h 41m
- When
- Every day
- Estimated price
- $250–950
Flights from Tocumen International Airport to San Diego International Airport via Denver
- Ave. Duration
- 11h 31m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,100
Flights from Tocumen International Airport to Tijuana International Airport via Guadalajara
- Ave. Duration
- 10h 57m
- When
- Every day
- Estimated price
- $220–850
Flights from Tocumen International Airport to Tijuana International Airport via Cancun
- Ave. Duration
- 8h 57m
- When
- Every day
- Estimated price
- $290–800
Flights from Tocumen International Airport to Tijuana International Airport via Mexico City
- Ave. Duration
- 10h 51m
- When
- Every day
- Estimated price
- $210–850
- Website
- united.com
Flights from Tocumen International Airport to San Diego International Airport
- Ave. Duration
- 6h 29m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $230–900
Flights from Tocumen International Airport to San Diego International Airport via Houston
- Ave. Duration
- 11h 35m
- When
- Every day
- Estimated price
- $250–950
Flights from Tocumen International Airport to San Diego International Airport via Los Angeles
- Ave. Duration
- 10h 41m
- When
- Every day
- Estimated price
- $250–950
Flights from Tocumen International Airport to San Diego International Airport via Denver
- Ave. Duration
- 11h 31m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,100
- Website
- aeromexico.com
Flights from Tocumen International Airport to Tijuana International Airport via Mexico City
- Ave. Duration
- 8h 30m
- When
- Every day
- Estimated price
- $210–850
Bus from Terminal Albrook to Terminal Tica Bus
- Ave. Duration
- 15h 30m
- Frequency
- 4 times a day
- Estimated price
- $58–90
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $60–90
- Phone
- +505 2222 2276
- [email protected]
- Website
- Nica Bus
Bus from Terminal NicaBus to Managua
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $37–38
- Website
- Nica Bus
- Phone
- +1 213 368 1172
- [email protected]
- Website
- busesusatours.com
Bus from Managua to Los Angeles
- Ave. Duration
- 4d 6h
- Frequency
- Once a week
- Estimated price
- $330–400
- Schedules at
- busesusatours.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Los Angeles to San Diego
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- Amtrak
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More Questions & Answers
Yes, the driving distance between Panama City to San Diego is 3723 miles. It takes approximately 3 days 2h to drive from Panama City to San Diego.
There are 1927+ hotels available in San Diego.








