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How to get fromPanama City to San Franciscoby plane, bus (Greyhound), car, or train

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There are 4 ways to get from Panama City to San Francisco by plane, bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to San Francisco International Airport (SFO)plane plane PTY - SFO
    10h 14m
    $457–650

  2. Fly to Norman Y. Mineta San José International Airport, Caltrain

    cheapest
    1. Fly from Tocumen International Airport (PTY) to Norman Y. Mineta San José International Airport (SJC)plane plane PTY - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    13h 13m
    $310–1,053

  3. Bus

    1. Take the bus from Terminal Albrook to Terminal Tica Busbus bus
    2. Take the bus from Terminal NicaBus to Managuabus bus
    3. Take the bus from Managua to Los Angelesbus bus
    4. Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus bus
    5d 17h
    $486–648

  4. Drive 4,161.7 mi

    1. Drive from Panama City to San Franciscocar car 4,161.7 mi
    3d 11h
    $917–1,324

Tocumen International Airport (PTY) to San Francisco International Airport (SFO) flights

Calendar24Weekly Planes
Duration9h 6mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Panama City to San Francisco.ExpandLaunch map view
  • Distance: 3,350.1 mi
  • Duration: 10h 14m

What companies run services between Panama City, Panama and San Francisco, CA, USA?

Copa Airlines and United Airlines fly from Tocumen International Airport (PTY) to San Francisco International Airport (SFO) 3 times a day. Alternatively, you can take a bus from Terminal Albrook to San Francisco Bus Station via Terminal Tica Bus, Terminal NicaBus, Managua, Los Angeles, Olympic / Union, Vignes / Cesar E Chavez, and Los Angeles Union Station in around 5d 17h.

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