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How to get fromPanama City to San Isidroby bus, car, plane, shuttle, or taxi

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There are 7 ways to get from Panama City to San Isidro by bus, car, plane, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Terminal Albrook to Uvitabus bus Panamá / ...
    12h 8m
    $50–71

  2. Drive 659.8 km

    1. Drive from Panama City to San Isidrocar car 659.8 km
    10h 20m
    $91–131

  3. Fly Albrook Marcos A. Gelabert International Airport to David, bus

    1. Fly from Albrook Marcos A. Gelabert International Airport (PAC) to David (DAV)plane plane PAC - DAV
    2. Take the bus from David to Fronterabus bus
    3. Take the bus from Paso Canoas to Uvitabus bus
    9h 12m
    $198–407

  4. Bus via Paso Canoas

    1. Take the bus from Terminal Tica Bus Panamá to Paso Canoasbus bus San José – Panamá
    2. Take the bus from Paso Canoas to San Isidro de El Generalbus bus By Cerro
    15h 16m
    $53–70

  5. Fly Tocumen International Airport to Juan Santamaría International Airport, bus, shuttle

    1. Fly from Tocumen International Airport (PTY) to Juan Santamaría International Airport (SJO)plane plane PTY - SJO
    2. Take the bus from Parada Aeropuerto - San José Lateral to Terminal TUASAbus bus
    3. Take a shuttle bus from San José to Dominicalshuttle bus
    4. Take the bus from Dominical to San Isidrobus bus
    9h 25m
    $217–815

  6. Fly Tocumen International Airport to Quepos La Managua Airport, taxi

    1. Fly from Tocumen International Airport (PTY) to Quepos La Managua Airport (XQP)plane plane PTY - XQP
    2. Take the taxi from Quepos-Airport-XQP to San Isidrotaxi taxi
    6h 40m
    $498–628

  7. Fly Tocumen International Airport to David, bus

    1. Fly from Tocumen International Airport (PTY) to David (DAV)plane plane PTY - DAV
    2. Take the bus from David to Fronterabus bus
    3. Take the bus from Paso Canoas to Uvitabus bus
    9h 39m
    $116–435

Panama City to San Isidro by bus and foot

Calendar8Weekly Services
Duration15h 16mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

Map of how to get from Panama City to San Isidro.ExpandLaunch map view
  • Distance: 668.5 km
  • Duration: 12h 8m

What companies run services between Panama City, Panama and San Isidro, Costa Rica?

Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter) operates a bus from Terminal Albrook to Uvita 4 times a day. Tickets cost $45–65 and the journey takes 10h 30m.

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