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How to get fromPanama City to Santiagoby plane, car, ferry, or bus

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There are 3 ways to get from Panama City to Santiago by plane, car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tocumen International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane PTY - SCL
    9h 21m
    $339–641

  2. Fly from Panama Pacific International Airport

    cheapest
    1. Fly from Panama Pacific International Airport (BLB) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane BLB - SCL
    9h 2m
    $268–773

  3. Drive, ferry, bus

    1. Drive from Panama City to Portobelocar car
    2. Take the ferry from Portobelo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus bus
    4. Take the bus from Cúcuta to Terminal San Borjabus bus
    10d 14h
    $1,190–1,304

Tocumen International Airport (PTY) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

Calendar67Weekly Planes
Duration8h 17mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

Map of how to get from Panama City to Santiago.ExpandLaunch map view
  • Distance: 4,845.3 km
  • Duration: 9h 21m

What companies run services between Panama City, Panama and Santiago, Chile?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Comodoro Arturo Merino Benítez International Airport (SCL) every 3 hours.

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