There are 8 ways to get from Panama City to Santiago by bus, car, taxi, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Fernandez de Cordoba
best- Take the bus from Panama City to Santiagobus David
3h 53m$9–18Bus
cheapest- Take the bus from Albrook to Santiagobus Panama City
4h 3m$6–24Drive 251.6 km
- Drive from Panama City to Santiagocar 251.6 km
3h 39m$35–50Taxi
- Take the taxi from Panama City to Santiagotaxi 251.6 km
3h 39m$140–170Fly Albrook Airport to Lago Bay, taxi
- Fly from Albrook Airport to Lago Bayplane
- Take the taxi from Lago Bay to Santiagotaxi
2h 24m$895–2,270Shuttle
- Take a shuttle bus from Panama City to Santiago
4h 3m$300Bus via Penonomé
- Take the bus from Panama Albrook to Penonomébus
- Take the bus from Penonomé to Santiago de Veraguasbus Panamá
4h 42m$18–27Fly Albrook Marcos A. Gelabert International Airport to Chitre, bus
- Fly from Albrook Marcos A. Gelabert International Airport (PAC) to Chitre (CTD)plane PAC - CTD
- Take the bus from Chitré to Ocubus
- Take the bus from Ocu to Santiagobus
4h 14m$146–153
Panama City to Santiago by bus
Questions & Answers
The cheapest way to get from Panama City to Santiago is to bus via Fernandez de Cordoba which costs $9 - $19 and takes 3h 53m.
The fastest way to get from Panama City to Santiago is to fly and taxi which takes 2h 24m and costs $850 - $2,300.
Yes, there is a direct bus departing from Albrook and arriving at Santiago. Services depart four times a day, and operate every day. The journey takes approximately 4h 3m.
The distance between Panama City and Santiago is 256 km. The road distance is 251.6 km.
The best way to get from Panama City to Santiago without a car is to bus via Fernandez de Cordoba which takes 3h 53m and costs $9 - $19.
It takes approximately 3h 53m to get from Panama City to Santiago, including transfers.
Panama City to Santiago bus services, operated by Panama Local Buses, depart from Panama City station.
Panama City to Santiago bus services, operated by Panama Local Buses, arrive at Santiago station.
Yes, the driving distance between Panama City to Santiago is 252 km. It takes approximately 3h 39m to drive from Panama City to Santiago.
There are 20+ hotels available in Santiago.
What companies run services between Panama City, Panama and Santiago, Panama?
Panama Local Buses operates a bus from Panama City to Santiago hourly. Tickets cost $18 and the journey takes 3h 42m. Three other operators also service this route.
- Website
- airpanama.com
Flights from Albrook Marcos A. Gelabert International Airport to Chitre
- Ave. Duration
- 30 min
- When
- Tuesday to Friday
- Estimated price
- $29–230
Bus from Panama City to Santiago
- Ave. Duration
- 3h 42m
- Frequency
- Hourly
- Estimated price
- $18
Bus from Panama City to Santiago
- Ave. Duration
- 4h
- Frequency
- Every 2 hours
- Estimated price
- $14
- Schedules at
- Transporte Panama Chiriqui Frontera S.A (Panachif)
- Phone
- +507958-6484
- Website
- Expreso Veraguense
Bus from Panama City to Santiago
- Ave. Duration
- 4h 30m
- Frequency
- Hourly
- Estimated price
- $9
- Schedules at
- Expreso Veraguense
- Phone
- +507 314 6231
- Website
- Vepasa Sanpasa
Bus from Panama City to Santiago
- Ave. Duration
- 6h
- Frequency
- Every 5 minutes
- Estimated price
- $11
- Website
- Vepasa Sanpasa
- Phone
- +507 6687 1802
- [email protected]
- Website
- Valitours Transportation
Shuttle from Panama City to Santiago
- Ave. Duration
- 4h 3m
- Frequency
- On demand
- Estimated price
- $300
- Website
- Valitours Transportation
- Phone
- +507 775-2974
- [email protected]
- Website
- Terminales Panama David
Bus from Albrook to Santiago
- Ave. Duration
- 4h 3m
- Frequency
- Hourly
- Estimated price
- $13
- Schedules at
- Terminales Panama David
- Phone
- +507 303 6326
- [email protected]
- Website
- Tranceibosa Bocas del Toro
Bus from Albrook to Santiago
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $6–24
- Schedules at
- Tranceibosa Bocas del Toro
- Child
- $6–8
- Adult
- $12–15
- Phone
- +507 303-6466
Bus from Panama Albrook to Penonomé
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- $6
Bus from Panama Albrook to Penonomé
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $11–16
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $11–16
Bus from Penonomé to Santiago de Veraguas
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–11
- Schedules at
- Cristóbal Colón Autobuses (Línea Dorada y Trans Galgos Inter)
- Road
- $7–11
Bus from Chitré to Ocu
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- $3
Bus from Ocu to Santiago
- Ave. Duration
- 1h
- Frequency
- Every 20 minutes
- Estimated price
- $2
- Ave. Duration
- 2h 39m
- Estimated price
- $55–170
Radio Taxi Concordia 24 hrs
- Phone
- +507 236-7848
- Website
- rtconcordia.amawebs.com
Radio Taxi Italia
- Phone
- +507 270-3066
Yellow Car
- Phone
- +507 396-9999
- Website
- facebook.com
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