How to get fromPanama City to Santo Domingoby plane, shuttle, or bus

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There are 4 ways to get from Panama City to Santo Domingo by plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly Tocumen International Airport to Las Américas International Airport
best
1. Fly from Tocumen International Airport (PTY) to Las Américas International Airport (SDQ)plane PTY - SDQ
5h 54m
$378–618
Fly Panama Pacific International Airport to Las Américas International Airport
cheapest
1. Fly from Panama Pacific International Airport (BLB) to Las Américas International Airport (SDQ)plane BLB - SDQ
6h 1m
$337–900
Fly Tocumen International Airport to Punta Cana International Airport, shuttle
1. Fly from Tocumen International Airport (PTY) to Punta Cana International Airport (PUJ)plane PTY - PUJ
2. Take a shuttle bus from Punta Cana Airport to Santo Domingoshuttle
7h 19m
$453–733
Fly Tocumen International Airport to Cibao International Airport, bus
1. Fly from Tocumen International Airport (PTY) to Cibao International Airport (STI)plane PTY - STI
2. Take the bus from La Vega to Santo Domingobus
7h 26m
$1,031–4,694

Tocumen International Airport (PTY) to Las Américas International Airport (SDQ) flights

35Weekly Planes

2h 30mAverage Duration

$95Cheapest Price

Questions & Answers

Map of how to get from Panama City to Santo Domingo.

Launch map view

Distance: 1,528.9 km
Duration: 5h 54m

What companies run services between Panama City, Panama and Santo Domingo, Dominican Republic?

Copa Airlines flies from Tocumen International Airport (PTY) to Las Américas International Airport (SDQ) 5 times a day.

Airlines

Bus operators

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Santo Domingo(opens in a new window), Dominican Republic(opens in a new window)

Santo Domingo, once known as Santo Domingo de Guzmán, known as Ciudad Trujillo between 1936 and 1961, is the capital and largest city of the Dominican Republic and the largest metropolitan area in the Caribbean by population. the city and immediate surrounding area (the Distrito Nacional) had a population of 1,029,110 while the total population is 3,798,699 when including Greater Santo Domingo (the "metropolitan area"). The city is coterminous with the boundaries of the Distrito Nacional ("D.N.", "National District"), itself bordered on three sides by Santo Domingo Province.

Places to stay in Santo Domingo

Barceló Santo Domingo(Opens in a new window)

8.2Very Good

Hodelpa Nicolás de Ovando(Opens in a new window)

8.5Very Good

Hodelpa Caribe Colonial(Opens in a new window)

8.1Very Good

Billini Hotel, Historic Luxury(Opens in a new window)

8.4Very Good

Rome2Rio makes travelling from Panama City to Santo Domingo easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Panama City to Santo Domingo right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.