Rome2Rio

How to get fromPanama City to St. Louisby plane or car

Find Transport to St. Louis

See all options

There are 3 ways to get from Panama City to St. Louis by plane or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tocumen International Airport

    best
    1. Fly from Tocumen International Airport (PTY) to Lambert–St. Louis International Airport (STL)plane plane PTY - STL
    10h 6m
    $281–1,041

  2. Fly from Panama Pacific International Airport

    cheapest
    1. Fly from Panama Pacific International Airport (BLB) to Lambert–St. Louis International Airport (STL)plane plane BLB - STL
    11h 52m
    $250–973

  3. Drive  3,470.7 mi

    1. Drive from Panama City to St. Louiscar car 3,470.7 mi
    3d
    $765–1,104

Tocumen International Airport (PTY) to Lambert–St. Louis International Airport (STL) flights

Calendar32Weekly Planes
Duration7h 29mAverage Duration
Ticket$243Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Panama City to St. Louis.ExpandLaunch map view
  • Distance: 2,189.4 mi
  • Duration: 10h 6m

What companies run services between Panama City, Panama and St. Louis, MO, USA?

American Airlines, Delta, and four other airlines fly from Tocumen International Airport (PTY) to Lambert–St. Louis International Airport (STL) 5 times a day.

Airlines

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides