Panama travel plans with the routes already figured out
Rome2Rio itineraries for Panama are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.
7 days in Panama
Panama City SantiagoItinerary navigation
Day 1: Panama City, Panama
Activities
- El Valle de Anton
- Gamboa Rainforest Resort Aerial Tram
Hotel
RecommendedHotel
Day 2: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Panama Canal Railway Scenic Ride
- Playa Langosta
Hotel
RecommendedHotel
Days 3–5: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Colón to Tocumenbus
- Take the bus from Colón to Tocumenbus
2h 24m
$4–6
Activities
- Amador Causeway
- Casco Viejo Historic District
Hotel
RecommendedHotel
Day 6: David, Panama
Distance
PopularTransport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 22m
$95–640
Activities
- Explore Boquete Town
- Volcan Baru National Park Hike
Hotel
RecommendedHotel
Day 7: Santiago, Panama
Distance
PopularTransport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Catedral Santiago Apostol
- Cascada El Salto
Hotel
RecommendedHotel
8 days in Panama
Panama City PenonoméItinerary navigation
Day 1: Panama City, Panama
Activities
- Causeway Islands
- Casco Viejo
Hotel
RecommendedHotel
Day 2: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Panama Canal Railway Scenic Ride
- Fuerte Sherman
Hotel
RecommendedHotel
Days 3–5: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Colón to Tocumenbus
- Take the bus from Colón to Tocumenbus
2h 24m
$4–6
Activities
- Biomuseo
- Mercado de Mariscos Seafood Market
Hotel
RecommendedHotel
Day 6: David, Panama
Distance
PopularTransport
- Fly from Tocumen to Davidplane
- Take the taxi from Tocumen to Davidtaxi
1h 22m
$95–640
Activities
- Museo de Historia y Arte Jose de Obaldia
- Volcan Baru National Park Hike
Hotel
RecommendedHotel
Day 7: Santiago, Panama
Distance
PopularTransport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Cascada El Salto
- Mercado Publico de Santiago
Hotel
RecommendedHotel
Day 8: Penonomé, Panama
Distance
PopularTransport
- Take the bus from Santiago to Penonomébus
1h 37m
$4–24
Activities
- Museo de Penonome
- Local Fonda Dining Experience
Hotel
RecommendedHotel
