Panama travel plans with the routes already figured out
Rome2Rio itineraries for Panama are made from a decade of travellers telling us their favourite ways to get from A to B. Personalise these itineraries to take you from A to B to C... and then all the way back home.
7 days in Panama
Panama City TocumenItinerary navigation
Day 1: Panama City, Panama
Activities
- Gamboa Rainforest Resort Aerial Tram
- National Theatre of Panama
Hotel
RecommendedHotel
Day 2: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Portobelo National Park
- Isla Grande Day Trip
Hotel
RecommendedHotel
Day 3: David, Panama
Distance
PopularTransport
- Take the bus from Colón to Davidbus
- Take the transfer from Colón to Davidtransfer
- Fly from Colón to Davidplane
- Take the taxi from Colón to Davidtaxi
3h 22m
$257–561
Activities
- Boquete Hot Springs
- Coffee Farm Tour Boquete
Hotel
RecommendedHotel
Day 4: Santiago, Panama
Distance
PopularTransport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Cascada El Salto
- Mercado Publico de Santiago
Hotel
RecommendedHotel
Day 5: Penonomé, Panama
Distance
PopularTransport
- Take the bus from Santiago to Penonomébus
1h 37m
$4–24
Activities
- Museo de Penonome
- Parque 8 de Diciembre
Hotel
RecommendedHotel
Days 6–7: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Penonomé to Tocumenbus
- Take the transfer from Penonomé to Tocumentransfer
- Take the subway from Penonomé to Tocumensubway
- Take the subway from Penonomé to Tocumensubway
2h 48m
$18–24
Activities
- Gamboa Rainforest Resort Activities
- Biomuseo
Hotel
RecommendedHotel
8 days in Panama
Panama City TocumenItinerary navigation
Day 1: Panama City, Panama
Activities
- Metropolitan Natural Park
- El Valle de Anton
Hotel
RecommendedHotel
Day 2: Colón, Panama
Distance
PopularTransport
- Take the bus from Panama City to Colónbus
1h 15m
$2–6
Activities
- Statue of Christopher Columbus
- Paseo Washington
Hotel
RecommendedHotel
Day 3: David, Panama
Distance
PopularTransport
- Take the bus from Colón to Davidbus
- Take the transfer from Colón to Davidtransfer
- Fly from Colón to Davidplane
- Take the taxi from Colón to Davidtaxi
3h 22m
$257–561
Activities
- Parque Miguel de Cervantes Saavedra
- Isla Parida Boat Trip
Hotel
RecommendedHotel
Day 4: Santiago, Panama
Distance
PopularTransport
- Take the bus from David to Santiagobus
2h 30m
$15–35
Activities
- Cascada El Salto
- Cerro La Cruz
Hotel
RecommendedHotel
Day 5: Penonomé, Panama
Distance
PopularTransport
- Take the bus from Santiago to Penonomébus
1h 37m
$4–24
Activities
- Cerro La Cruz Viewpoint
- Chorro de Ola Waterfalls
Hotel
RecommendedHotel
Days 6–8: Tocumen, Panama
Distance
PopularTransport
- Take the bus from Penonomé to Tocumenbus
- Take the transfer from Penonomé to Tocumentransfer
- Take the subway from Penonomé to Tocumensubway
- Take the subway from Penonomé to Tocumensubway
2h 48m
$18–24
Activities
- Gamboa Rainforest Resort Activities
- Mercado de Mariscos Seafood Market
Hotel
RecommendedHotel