There are 4 ways to get from Panama to Guayaquil by plane, car, ferry, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from David
best- Fly from David (DAV) to José Joaquín De Olmedo International Airport (GYE)plane DAV - GYE
5h 13m$143–704Drive, ferry, bus, taxi
- Drive from Panama City to Portobelocar
- Take the ferry from Portobelo to Cartagenaferry
- Take the bus from Terminal de Transporte de Cartagena to Terminal del Nortebus
- Take the taxi from Medellín to Rumichacataxi
- Take the bus from Tulcán to Terminal Terrestre de Guayaquilbus
7d 21h$1,525–1,553Fly from Tocumen International Airport
- Fly from Tocumen International Airport (PTY) to José Joaquín De Olmedo International Airport (GYE)plane PTY - GYE
4h 43m$270–520Drive, ferry, bus
- Drive from Panama City to Puerto Lindocar
- Take the ferry from Puerto Lindo to Cartagenaferry
- Take the bus from Terminal de Transporte de Cartagena to Terminal Salitrebus
- Take the bus from Terminal Salitre to Terminales de Transportes de Ipialesbus
- Take the bus from Tulcán to Ibarrabus
- Take the bus from Ibarra to Terminal Terrestre de Guayaquilbus
8d 14h$830–921
David (DAV) to José Joaquín De Olmedo International Airport (GYE) flights
Comparing Your Travel Options
The cheapest way to get from Panama to Guayaquil is to fly which costs $140 - $750 and takes 5h 13m.
The fastest way to get from Panama to Guayaquil is to fly which takes 4h 43m and costs $270 - $550.
The distance between Panama and Guayaquil is 1210 km.
It takes approximately 5h 13m to get from Panama to Guayaquil, including transfers.
There are 412+ hotels available in Guayaquil.
What companies run services between Panama and Guayaquil, Ecuador?
Copa Airlines flies from David (DAV) to José Joaquín De Olmedo International Airport (GYE) twice daily.
- Website
- copaair.com
Flights from David to José Joaquín De Olmedo International Airport via Tocumen International Airport
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $140–700
Flights from Tocumen International Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $75–410
- Website
- avianca.com
Flights from Tocumen International Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $230–480
- Phone
- 01 800 051 8001
- [email protected]
- Website
- expresobrasilia.com
Bus from Terminal de Transporte de Cartagena to Terminal del Norte
- Ave. Duration
- 11h 38m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- $35–55
- Phone
- +57 604 444 8888
- [email protected]
- Website
- rapidoochoa.com.co
Bus from Terminal de Transporte de Cartagena to Terminal del Norte
- Ave. Duration
- 13h
- Frequency
- 5 times a day
- Estimated price
- $35–55
- Schedules at
- rapidoochoa.com.co
- Book at
- rapidoochoa.com.co
- Phone
- +593 95 885 1254
- [email protected]
- Website
- microsancristobal.com
Bus from Tulcán to Terminal Terrestre de Guayaquil
- Ave. Duration
- 13h
- Frequency
- Every 4 hours
- Estimated price
- $19–22
- Book at
- busplace.com
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal de Transporte de Cartagena to Terminal Salitre
- Ave. Duration
- 23h
- Frequency
- Every 3 hours
- Estimated price
- $60–85
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $60–85
- Phone
- +57 310 7883333
- [email protected]
- Website
- concordeoficial.com
Bus from Terminal de Transporte de Cartagena to Terminal Salitre
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $40–95
- Schedules at
- concordeoficial.com
- Book at
- concordeoficial.com
- Phone
- +57 601 424 9090
- [email protected]
- Website
- continentalbus.com.co
Bus from Terminal Salitre to Terminales de Transportes de Ipiales
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $59
- Schedules at
- continentalbus.com.co
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminal Salitre to Terminales de Transportes de Ipiales
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $55–80
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +593 062980728
- [email protected]
- Website
- Cooperativa Tax Gacela
Bus from Tulcán to Ibarra
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- $3–7
- Schedules at
- Cooperativa Tax Gacela
Bus from Tulcán to Ibarra
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Website
- Compañía Expreso Turismo del Norte
- Phone
- +593 98 875 2804
- [email protected]
- Website
- Cooperativa de Transportes Aerotaxi
Bus from Ibarra to Terminal Terrestre de Guayaquil
- Ave. Duration
- 9h 10m
- Frequency
- Hourly
- Estimated price
- $15–16
- Website
- Cooperativa de Transportes Aerotaxi
- Website
- Cooperativa de Transportes Aerotaxi
- Phone
- +57 310 704 0425
- [email protected]
- Website
- Blue Sailing
Ferry from Puerto Lindo to Cartagena
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
- Ave. Duration
- 16h 40m
- Estimated price
- $755
Tax Individual
- Phone
- +57 604 444 4444
- Website
- tax-individual.com.co
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