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How to get fromPanama to Guayaquilby plane, car, ferry, bus, or taxi

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There are 4 ways to get from Panama to Guayaquil by plane, car, ferry, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from David

    best
    1. Fly from David (DAV) to José Joaquín De Olmedo International Airport (GYE)plane plane DAV - GYE
    5h 14m
    $153–704

  2. Drive, ferry, bus, taxi

    1. Drive from Panama City to Portobelocar car
    2. Take the ferry from Portobelo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal del Nortebus bus
    4. Take the taxi from Medellín to Rumichacataxi taxi
    5. Take the bus from Rumichaca to Terminal Terrestre Quitumbebus bus
    6. Take the bus from Terminal Terrestre Quitumbe to Guayaquilbus bus
    7d 22h
    $1,560–1,608

  3. Fly from Tocumen International Airport

    1. Fly from Tocumen International Airport (PTY) to José Joaquín De Olmedo International Airport (GYE)plane plane PTY - GYE
    4h 44m
    $240–490

  4. Drive, ferry, bus

    1. Drive from Panama City to Puerto Lindocar car
    2. Take the ferry from Puerto Lindo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal Salitrebus bus
    4. Take the bus from Terminal Salitre to Terminales de Transportes de Ipialesbus bus
    5. Take the bus from Rumichaca to Terminal Terrestre Quitumbebus bus
    6. Take the bus from Terminal Terrestre Quitumbe to Duránbus bus
    8d 18h
    $866–960

David (DAV) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar13Weekly Planes
Duration5h 59mAverage Duration
Ticket$150Cheapest Price
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Questions & Answers

Map of how to get from Panama to Guayaquil.ExpandLaunch map view
  • Distance: 1,210.2 km
  • Duration: 5h 14m

What companies run services between Panama and Guayaquil, Ecuador?

Copa Airlines flies from David (DAV) to José Joaquín De Olmedo International Airport (GYE) twice daily.

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