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How to get fromPanama to Guayaquilby plane, car, ferry, bus, or taxi

Find Transport to Guayaquil

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There are 4 ways to get from Panama to Guayaquil by plane, car, ferry, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from David

    best
    1. Fly from David (DAV) to José Joaquín De Olmedo International Airport (GYE)plane plane DAV - GYE
    5h 13m
    $143–704
  2. Drive, ferry, bus, taxi

    1. Drive from Panama City to Portobelocar car
    2. Take the ferry from Portobelo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal del Nortebus bus
    4. Take the taxi from Medellín to Rumichacataxi taxi
    5. Take the bus from Tulcán to Terminal Terrestre de Guayaquilbus bus
    7d 21h
    $1,525–1,553
  3. Fly from Tocumen International Airport

    1. Fly from Tocumen International Airport (PTY) to José Joaquín De Olmedo International Airport (GYE)plane plane PTY - GYE
    4h 43m
    $270–520
  4. Drive, ferry, bus

    1. Drive from Panama City to Puerto Lindocar car
    2. Take the ferry from Puerto Lindo to Cartagenaferry ferry
    3. Take the bus from Terminal de Transporte de Cartagena to Terminal Salitrebus bus
    4. Take the bus from Terminal Salitre to Terminales de Transportes de Ipialesbus bus
    5. Take the bus from Tulcán to Ibarrabus bus
    6. Take the bus from Ibarra to Terminal Terrestre de Guayaquilbus bus
    8d 14h
    $830–921

David (DAV) to José Joaquín De Olmedo International Airport (GYE) flights

Calendar13Weekly Planes
Duration6h 3mAverage Duration
Ticket$140Cheapest Price
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Comparing Your Travel Options

What companies run services between Panama and Guayaquil, Ecuador?

Copa Airlines flies from David (DAV) to José Joaquín De Olmedo International Airport (GYE) twice daily.

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