There are 4 ways to get from Panama to Manaus by plane, car, ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Tocumen International Airport
best- Fly from Tocumen International Airport (PTY) to Manaus (MAO)plane PTY - MAO
6h 52mR$1,623–5,723Fly from David
cheapest- Fly from David (DAV) to Manaus (MAO)plane DAV - MAO
7h 29mR$1,218–5,521Drive, ferry, bus
- Drive from Panama City to Portobelocar
- Take the ferry from Portobelo to Cartagenaferry
- Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
- Take the bus from Terminal Cúcuta to Terminal San Cristóbalbus
- Take the bus from Terminal Expresos Los Llanos San Cristobal to Puerto La Cruzbus
- Take the bus from Puerto la Cruz to Manausbus
10d 18hR$5,353–5,864Drive, ferry, bus via Mérida
- Drive from Panama City to Portobelocar
- Take the ferry from Portobelo to Cartagenaferry
- Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
- Take the bus from Ureña to Terminal Jose Antonio Paredesbus
- Take the bus from Terminal Jose Antonio Paredes to Puerto La Cruzbus
- Take the bus from Puerto la Cruz to Manausbus
11d 7hR$5,359–5,940
Tocumen International Airport (PTY) to Manaus (MAO) flights
Comparing Your Travel Options
The cheapest way to get from Panama to Manaus is to fly which costs R$ 1200 - R$ 5500 and takes 7h 29m.
The fastest way to get from Panama to Manaus is to fly which takes 6h 52m and costs R$ 1600 - R$ 6000.
The distance between Panama and Manaus is 2561 km.
It takes approximately 6h 52m to get from Panama to Manaus, including transfers.
Manaus is 1h ahead of Panama. It is currently 9:29 PM in Panama and 10:29 PM in Manaus.
There are 634+ hotels available in Manaus.
What companies run services between Panama and Manaus, Brazil?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Tocumen International Airport (PTY) to Manaus (MAO) twice daily.
- Website
- copaair.com
Flights from Tocumen International Airport to Manaus
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- R$700–3,300
Flights from David to Manaus via Tocumen International Airport
- Ave. Duration
- 6h 54m
- When
- Thursday and Friday
- Estimated price
- R$1,200–5,500
- Website
- avianca.com
Flights from Tocumen International Airport to Manaus via Bogota
- Ave. Duration
- 7h 50m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- R$1,300–4,500
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal de Transporte de Cartagena to Terminal Cúcuta
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- R$237–350
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- R$260–350
Bus from Terminal de Transporte de Cartagena to Terminal Cúcuta
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- R$237–350
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- R$260–350
- Phone
- 01 800 051 8001
- [email protected]
- Website
- expresobrasilia.com
Bus from Terminal de Transporte de Cartagena to Terminal Cúcuta
- Ave. Duration
- 17h 2m
- Frequency
- Twice daily
- Estimated price
- R$220–347
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- R$220–310
Bus from Terminal de Transporte de Cartagena to Terminal Cúcuta
- Ave. Duration
- 17h 2m
- Frequency
- Twice daily
- Estimated price
- R$220–347
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- R$220–310
Bus from Terminal Cúcuta to Terminal San Cristóbal
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- R$34
- Phone
- +58 424 719 6069
- [email protected]
- Website
- Expresos Los Llanos
Bus from Terminal Expresos Los Llanos San Cristobal to Puerto La Cruz
- Ave. Duration
- 18h
- Frequency
- Twice daily
- Estimated price
- R$240–330
- Schedules at
- Expresos Los Llanos
- Buscama
- R$240–330
- Phone
- +58 424 855 1500
- [email protected]
- Website
- Expresos Sol y Mar 2023
Bus from Puerto la Cruz to Manaus
- Ave. Duration
- 3d
- Frequency
- 3 times a week
- Estimated price
- R$850–1,100
- Website
- Expresos Sol y Mar 2023
- Convencional
- R$850–1,100
Bus from Puerto la Cruz to Manaus
- Ave. Duration
- 3d
- Frequency
- 3 times a week
- Estimated price
- R$850–1,100
- Website
- Expresos Sol y Mar 2023
- Convencional
- R$850–1,100
Bus from Ureña to Terminal Jose Antonio Paredes
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- R$110–140
- Schedules at
- instagram.com
- Convencional
- R$110–140
- Phone
- +58 424 7002099
- Website
- Expresos Merida C.A.
Bus from Terminal Jose Antonio Paredes to Puerto La Cruz
- Ave. Duration
- 24h
- Frequency
- Once a week
- Estimated price
- R$200–336
- Schedules at
- Expresos Merida C.A.
- Buscama
- R$200–280
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Best ways to travel around Australia, Need to know: Jadrolinija, and The London Underground: Essential tips to navigate the Tube - to help you get the most out of your next trip.