How to get fromPanama to Santiagoby plane, car, ferry, or bus

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There are 3 ways to get from Panama to Santiago by plane, car, ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from David
best
1. Fly from David (DAV) to Comodoro Arturo Merino Benítez International Airport (SCL)plane DAV - SCL
9h 15m
$364–1,307
Fly from Tocumen International Airport
cheapest
1. Fly from Tocumen International Airport (PTY) to Comodoro Arturo Merino Benítez International Airport (SCL)plane PTY - SCL
9h 27m
$351–593
Drive, ferry, bus
1. Drive from Panama City to Portobelocar
2. Take the ferry from Portobelo to Cartagenaferry
3. Take the bus from Terminal de Transporte de Cartagena to Terminal Cúcutabus
4. Take the bus from Cúcuta to Terminal San Borjabus
10d 14h
$1,190–1,309

David (DAV) to Comodoro Arturo Merino Benítez International Airport (SCL) flights

9Weekly Planes

9h 14mAverage Duration

$361Cheapest Price

Questions & Answers

Map of how to get from Panama to Santiago.

Launch map view

Distance: 4,823.8 km
Duration: 9h 15m

What companies run services between Panama and Santiago, Chile?

Copa Airlines flies from David (DAV) to Comodoro Arturo Merino Benítez International Airport (SCL) once daily.

Airlines

Bus operators

Ferry operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Southend Airport into central London, South Korea: Travelling from Seoul to Busan , and How to get from JFK to New York City - to help you get the most out of your next trip.

Santiago(opens in a new window), Chile(opens in a new window)

Santiago, also known as Santiago de Chile, is the capital and largest city of Chile and one of the largest cities in the Americas. It is located in the country's central valley and is the center of the Santiago Metropolitan Region, which has a population of 7 million, representing 40% of Chile's total population. Most of the city is situated between above sea level.

Things to do in Santiago

Fantasilandia(Opens in a new window)

Fantasilandia is a Chilean amusement park. The park opened in 1978 and is located in a corner of O'Higgins Park in Santiago, Chile.

Places to stay in Santiago

Hotel Plaza San Francisco(Opens in a new window)

8.9Fabulous

Hotel Cumbres Lastarria(Opens in a new window)

9.0Fabulous

Hotel Luciano K(Opens in a new window)

8.6Fabulous

Plaza Huelen(Opens in a new window)

9.3Superb

Rome2Rio makes travelling from Panama to Santiago easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Panama to Santiago right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.