Rome2Rio

How to get fromPenn State University (Station) to Chicagoby bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

Find Transport to Chicago

See all options

There are 8 ways to get from Penn State University (Station) to Chicago by bus, plane, bus (Flixbus), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 117 bus to Philadelphia International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Penn State University to Chester Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    5h 20m
    $157–383

  2. Line 117 bus to Philadelphia International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Penn State University to Chester Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    5h 49m
    $127–203

  3. Bus (Flixbus)

    1. Take the bus from Philadelphia Bus Station to Chicago Bus Stationbus bus FlixBus N2642
    22h
    $145–228

  4. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Washington Union Station to Chicago Union Stationtrain train Floridian / ...
    22h 38m
    $456–1,308

  5. Drive  741.4 mi

    1. Drive from Penn State University (Station) to Chicagocar car 741.4 mi
    12h 14m
    $136–196

  6. Train to Baltimore-Washington International Airport, fly to Chicago Midway International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    7h 15m
    $172–963

  7. Bus via Baltimore

    1. Take the bus from Philadelphia Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0320 / ...
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    23h 45m
    $150–235

  8. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    29h 7m
    $555–908

Penn State University (Station) to Chicago by bus and subway (Flixbus)

Calendar3Weekly Services
Duration22hAverage Duration
Ticket$145Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Penn State University (Station) to Chicago.ExpandLaunch map view
  • Distance: 698.2 mi
  • Duration: 5h 20m

What companies run services between Penn State University (Station), PA, USA and Chicago, IL, USA?

Flixbus USA operates a bus from Philadelphia Bus Station to Chicago Bus Station 3 times a week. Tickets cost $140–220 and the journey takes 20h. Alternatively, you can take a bus from Penn State University to Chicago Union Station via Baltimore Pk & Orange St, Media, 30th Street Station, and Washington Union Station in around 22h 38m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There