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How to get fromPennsylvania to Chicagoby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Greyhound)

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There are 11 ways to get from Pennsylvania to Chicago by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Erie International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Erie International Airport (ERI) to Chicago O'Hare International Airport (ORD)plane plane ERI - ORD
    4h 18m
    $44–267

  2. Bus

    1. Take the bus from Philadelphia Bus Station to Newark Penn Stationbus bus FlixBus 2601 / ...
    2. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus FlixBus N2641 / ...
    19h 10m
    $132–233

  3. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    21h 20m
    $275–1,146

  4. Drive 758.2 mi

    1. Drive from Philadelphia to Chicagocar car 758.2 mi
    12h 27m
    $139–200

  5. Fly Philadelphia International Airport to Chicago Midway International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    4h 8m
    $145–408

  6. Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    4h 14m

  7. Bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    4h 41m

  8. Fly Lehigh Valley International Airport to Chicago O'Hare International Airport

    1. Fly from Lehigh Valley International Airport (ABE) to Chicago O'Hare International Airport (ORD)plane plane ABE - ORD
    4h 33m
    $59–307

  9. Fly Philadelphia International Airport to Chicago O'Hare International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    4h 36m
    $90–458

  10. Bus via Baltimore (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Baltimore Greyhound Garagebus bus Greyhound US0305
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    24h 40m
    $137–270

  11. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    28h 14m
    $343–703

Pennsylvania to Chicago by bus

Calendar15Weekly Buses
Duration19h 10mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Pennsylvania to Chicago.ExpandLaunch map view
  • Distance: 428.7 mi
  • Duration: 4h 18m

What companies run services between Pennsylvania, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Erie International Airport (ERI) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a bus from Philadelphia Bus Station to Chicago Bus Station via Newark Penn Station in around 19h 10m.

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