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How to get fromPennsylvania to Florenceby bus (Flixbus, Greyhound), train (Amtrak), car, plane, bus, bus (Greyhound), or train

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There are 10 ways to get from Pennsylvania to Florence by bus (Flixbus, Greyhound), train (Amtrak), car, plane, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Washington

    best
    1. Take the bus from Philadelphia Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus
    3. Take the bus from Fayetteville Bus Station to Florence Bus Stationbus bus
    12h 49m
    $84–155

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Philadelphia Bus Station to Raleigh Bus Stationbus bus Greyhound US0670
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    13h 24m
    $83–159

  3. Train (Amtrak)

    1. Take the train from 30th Street Station to Florence Stationtrain train Palmetto / ...
    14h 13m
    $173–363

  4. Drive 535.6 mi

    1. Drive from Philadelphia to Florencecar car 535.6 mi
    9h 23m
    $98–142

  5. Fly Philadelphia International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Philadelphia International Airport (PHL) to Charlotte Douglas International Airport (CLT)plane plane PHL - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    8h 35m
    $135–236

  6. Fly Pittsburgh International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Pittsburgh International Airport (PIT) to Charlotte Douglas International Airport (CLT)plane plane PIT - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 5m
    $113–585

  7. Fly Philadelphia International Airport to Myrtle Beach, bus, train

    1. Fly from Philadelphia International Airport (PHL) to Myrtle Beach (MYR)plane plane PHL - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 15m
    $129–531

  8. Fly Philadelphia International Airport to Columbia, bus

    1. Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane plane PHL - CAE
    2. Take the bus from Columbia, SC to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 28m
    $262–1,361

  9. Fly Lehigh Valley International Airport to Myrtle Beach, bus, train

    1. Fly from Lehigh Valley International Airport (ABE) to Myrtle Beach (MYR)plane plane ABE - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 4m
    $113–420

  10. Fly Pittsburgh International Airport to Myrtle Beach, bus, train

    1. Fly from Pittsburgh International Airport (PIT) to Myrtle Beach (MYR)plane plane PIT - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 43m
    $232–862

Pennsylvania to Florence by bus

Calendar14Weekly Buses
Duration12h 49mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Pennsylvania to Florence.ExpandLaunch map view
  • Distance: 550.2 mi
  • Duration: 12h 49m

What companies run services between Pennsylvania, USA and Florence, SC, USA?

You can take a bus from Philadelphia Bus Station to Florence Bus Station via Washington Union Station and Fayetteville Bus Station in around 12h 49m. Alternatively, Amtrak operates a train from 30th Street Station to Florence Station twice daily. Tickets cost $170–360 and the journey takes 13h 11m.

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