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How to get fromPennsylvania to Illinoisby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Greyhound)

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There are 11 ways to get from Pennsylvania to Illinois by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Erie International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Erie International Airport (ERI) to Chicago O'Hare International Airport (ORD)plane plane ERI - ORD
    4h 18m
    $44–267

  2. Bus

    1. Take the bus from Philadelphia Bus Station to Harrisburg Bus Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    19h 30m
    $187–272

  3. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train Floridian
    21h 20m
    $275–1,146

  4. Drive 758.2 mi

    1. Drive from Philadelphia to Chicagocar car 758.2 mi
    12h 27m
    $139–200

  5. Fly Philadelphia International Airport to Chicago Midway International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago Midway International Airport (MDW)plane plane PHL - MDW
    4h 8m
    $145–408

  6. Bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    4h 14m

  7. Bus to Pittsburgh International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)plane plane PIT - ORD
    4h 41m

  8. Fly Lehigh Valley International Airport to Chicago O'Hare International Airport

    1. Fly from Lehigh Valley International Airport (ABE) to Chicago O'Hare International Airport (ORD)plane plane ABE - ORD
    4h 33m
    $59–334

  9. Fly Philadelphia International Airport to Chicago O'Hare International Airport

    1. Fly from Philadelphia International Airport (PHL) to Chicago O'Hare International Airport (ORD)plane plane PHL - ORD
    4h 37m
    $90–458

  10. Bus via Baltimore

    1. Take the bus from Spring Garden to Baltimorebus bus New York
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    23h 7m
    $193–283

  11. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    28h 14m
    $343–703

Pennsylvania to Illinois by bus

Calendar16Weekly Buses
Duration19h 30mAverage Duration
Ticket$187Cheapest Price
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Questions & Answers

Map of how to get from Pennsylvania to Illinois.ExpandLaunch map view
  • Distance: 428.7 mi
  • Duration: 4h 18m

What companies run services between Pennsylvania, USA and Illinois, USA?

American Airlines and United Airlines fly from Erie International Airport (ERI) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a bus from Philadelphia Bus Station to Chicago Bus Station via Harrisburg Bus Station in around 19h 30m.

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