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How to get fromPennsylvania to Missouriby bus, plane, bus (Greyhound), train (Amtrak), car, or train

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There are 10 ways to get from Pennsylvania to Missouri by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Lambert–St. Louis International Airport

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    4h 39m

  2. Fly Philadelphia International Airport to Lambert–St. Louis International Airport

    cheapest
    1. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    4h 34m
    $126–757

  3. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    25h 5m
    $213–317

  4. Train via Washington (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    29h 55m
    $685–1,677

  5. Drive  1,121.8 mi

    1. Drive from Philadelphia to Kansas Citycar car 1,121.8 mi
    19h 2m
    $199–287

  6. Bus to Cleveland-Hopkins International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Erie to Cleveland Bus Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    5h 42m
    $127–686

  7. Fly Philadelphia International Airport to Kansas City

    1. Fly from Philadelphia International Airport (PHL) to Kansas City (MCI)plane plane PHL - MCI
    6h 11m
    $213–1,104

  8. Train to Baltimore-Washington International Airport, fly to Lambert–St. Louis International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    6h 4m
    $150–1,307

  9. Bus, train

    1. Take the bus from Philadelphia Bus Station to Chicago Bus Stationbus bus FlixBus N2642
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    28h 44m
    $390–589

  10. Train (Amtrak)

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    36h 49m
    $793–1,274

Pennsylvania to Missouri by bus (Greyhound)

Calendar21Weekly Buses
Duration25h 5mAverage Duration
Ticket$213Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pennsylvania to Missouri.ExpandLaunch map view
  • Distance: 590.5 mi
  • Duration: 4h 39m

What companies run services between Pennsylvania, USA and Missouri, USA?

You can take a bus from Philadelphia Bus Station to Kansas City Bus Station via St Louis Bus Station in around 25h 5m. Alternatively, you can take a subway from 15th St/City Hall to Metro Center via Drexel Station at 30th St, 30th Street Station, Washington Union Station, Union Station, Red Line Center Platform, Rockville, Red Line Center Platform, Rockville Amtrak, Chicago Union Station, Kansas City, and Union Station in around 29h 55m.

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Need to know: Greyhound

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